<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26897

Description Uncharacterized protein
SequenceMLESWRQRLSPIEWSIKLYNGFSCKEDTENDFKIDPVELCEILLDQMNIGQSPSPLLASYLRYAISIKLIEYTDLFESVYKYSSISRPHHFSVILDILLDVVNIINFTHQNNSLVSNNVSTPTNNNNTVSKLIYSKVLSSPTFNSNKKQTNHNSNSSSIINSSSKLSSIENEQPSNNNINENNSNSNNNNNKGTSSNNNDSNGTLSSSSLSTPVSAMAGATNEHNFENSSTSNEENGVSSDNNSHRGENGTVQMNGITDHNHIGNKRKEMDTDENDDQNVHHLKKIKHDNEQPQITTTTTTTTTTTTTTTTTTTLDEGNLNFTTTNIYDKSQPKQQTPSSLLSSSLSFYNKQLLSFTKLATLLFKAIDFYYQEEEQIKLQQQYQQTNSNEPSTIANLNTNILFKNSSKSLEILSIIQNNSTFKSFIYLSKYQYTLTCFKDLVSTFVSTQNYLRDYLKNNQQQQPISSSQSQTAATPNSNPLSQLIKQKYQKLFLEFRMILVNKADILPTGDIIPLAHNQIHSDKPLVLSFEFIIEQEITGNSFKSFKTRDISHSNNNSLLNPSISNGNLVADSKDSNDLNSGGSSDVTIQDDASINNIGQQHSSLESQQKLQQQLQRIKQSKEVENVSDCFTKLLALKTIKSMTDIEFLLEIVKILFQKLVNCEPNSNKFKKTKLFLLFKVPQLYSIMKANNGHSDNSINKKDSNKSNKLNNPDDSINDGIMDSTDNTNSNENLDSNNINENGDAPNDGSINSSTNSNGIGKSIGSNSKGMNRKKASIDSYNVIETVLYQINQFPTLAQVEDNIVFSLIQILIKKHLVDIKLLKKLFSNYLTDIDSLDSEIQAPPSSELSFDNIHMLELHSLADVLKIKELIESLLNSTDPNNTSIMKKLFDFIKQYLVTPFDYQDKLLGVIFNILENIDYDSNKLLVMVAMYIFSDPLVIDCLDVHGYTLRLIMILINICETYGSTTYQQLLQDNPMYETEHNHNQKHLYFYFTIPFNLLYVLLFVLYDVKNNKYNLDLIKSKLLESNLKCNKFTNWLYYTIRDSNINNSNTNSANKESSFEYQFLKNLLESSFTDDGIEKFQTLSQKDYSSWDVVSGLPNILHNIFDCYDRNIIPDEKVTKTISLLFQYVPFSPIVIFDYLSKTKSTLFTSSPTTTTTSTTKSPNSTTTTTTTTTTSTTTTSNQLNKGNTTNSANNANNKPNQSASQQNGRPSTTGTNNNLSKRDKAISSIEACFWNLNENRLLFRLSDYHKSIVSEENINDLYKLFEPIFETTSLTLFPKTRKFSEFRYYSYHSTLFNPTYHTFLSPPAQLYTMSATVAIHQVIEQFLNKPSPDFLSLECEIKYILMRSSSNIYQIVNLVAKEIFDIILQSNQVESLYSVRAIELGGYILGSLVGVESLPIILNSIIPSWSEHIQSSYQGQLMAFFCFNIIIHSNAIYYIETDYSIRKSFKKFLLLLNDTMKRMYLVGPLNGVIAFALSFITLLIHFNNSTFNNCLQQSNSNNQQSQQQQQQISKLYNINNLNSNFSINTQMINQLYETVAKNIKSKKNLTILKQKQLQNEITLEQYQQKIQLFNQKQTELELCLQSQEQQLQKQKQLLHKQQSSLKSIFNILSTSQMEDLAISIQNLSNFFLAISIYDKNDLHNCLKLFKHK
Length1656
PositionTail
OrganismDictyostelium purpureum (Slime mold)
KingdomAmoebozoa
LineageEukaryota> Amoebozoa> Evosea> Eumycetozoa> Dictyostelia> Dictyosteliales> Dictyosteliaceae> Dictyostelium.
Aromaticity0.09
Grand average of hydropathy-0.472
Instability index47.66
Isoelectric point6.14
Molecular weight188321.15
Publications
PubMed=21356102

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26897
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|    1838.52|     583|     864|       1|     676|       1
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    1-  654 (799.92/431.25)	.......................MLESWRQRLSPIEWSI..KLyngFsckeDTENDFKIDPVELCEILLDQM.....NIGQSPSPLLASYLRYAISIKLIeyTDLFEsVYKYSsisrphhFSVILdILLDVVNIINFTHQNNsLVSNNVSTPTNNNNTVSKLIYsKVLSSPTFN......SNKKQTNHNSNS.....SSIINSSSKLSSIEN...EQPS.NNNINENNSNSNNNNNKGTSSNNNDSNGTLSSSSLStpvsamaGATNEHNFENSSTSNEENGVSSDNNShrgengtvqmNGITD..HNHIGNKRKEMDTDEN..DDQNV...................HHLKKIKHD....NEQPQITTTTTT.....TTTTTTTTTTTTTLDEGNL......NFT.TTNIYDKSQ..PKQQT......PSSL.LSSSLSFYNKQLLS....FTKLAT..LLFKAIDFYYQ..EEEQIklQQQYQQTnsnEPstianlntniLFKNSskSLEILSiiqNNSTFKSFIYlskYQYTLTCFKDLVSTFVSTQNYLRDYLKNNQQQQPIsssqSQTAATPNSNPLSQLIKQKYqklflefrmIL.............VNKaDILptgDIIpLAHNQIHS...........................DKpLVLSFEFIIEQEITGNSFKSFKTRDISHSN...............NN..SLLNPSISNGNLVAdskDSNDLNSGG...ssdvtiqDDASINNIG.QQHSSLE.....SQQKLQQQLQ....RIKQSKEVENVSDCFTklLALKTIKSMtdIEFLLEIVK
  655-  866 (207.96/65.69)	ILFQKLVNCEPNSNKF.KKTKLF..............................................................................................................................................LLFKVPQLY......SIMKANNGHSDN.....SINKKDSNKSNKLNN...PDDSiNDGIMDSTDNTNSNEN..LDSNNINENG...............DAPNDGSI.NSST...........NS..........NGI....GKSIGSNSKGMNRKKAsiDSYNV.....................IETVLYQ...iNQFPTLAQVEDN.....IVFSLIQILIKKHLVDIKLlkklfsNY..LTDI.DSLD..SEIQA......PP....SSELSFDNIHMLE....LHSLAD..VL...........................................................................................................................................................................................................................................................................................................................................................................
  871- 1548 (781.51/300.48)	.......................LIESLLNSTDPNNTSImkKL...F....DFIKQYLVTPFDYQDKLLGVIfnileNIDYDSNKLLVMVAMYIFSDPLV..IDCLD.VHGYT.......LRLIM.ILINICETYGSTTYQQ.LLQDNPMYETEHNHNQKHLYF..YFTIP.FNllyvllFVLYDVKNNKYNldlikSKLLESNLKCNKFTNwlyYTIR.DSNI..NNSNTNSA.NKE.SSFEYQFLKNLLESSFT...........DDGIEKFQTLSQKDYSSWDVVS...........GLPNilHNIFDC....YDRNII..PDEKVtktisllfqyvpfspivifDYLSKTK..stlfTSSPTTTTTSTTkspnsTTTTTTTTTTSTTTTSNQL......NKGnTTNSANNANnkPNQSAsqqngrPSTTgTNNNLSKRDKAISSieacFWNLNEnrLLFRLSDYHKSivSEENI..NDLYKLF...EP..........IFETT..SLTLFP...KTRKFSEFRY...YSYHSTLFNPTYHTFLSPPAQLYTMSATVAIHQVI....EQFLNKPSPDFLSLECEIKY.........ILmrsssniyqivnlVAK.EIF...DII.LQSNQVESlysvraielggyilgslvgveslpiilNS.IIPSWSEHIQSSYQGQLMAFFCFNIIIHSNaiyyietdysirksfKKflLLLNDTMKRMYLVG...PLNGVIAFAlsfitllihfNNSTFNNCL.QQSNS.......NNQQSQQQQQ....QISKLYNINNLNSNFS..INTQMINQL..YETVAKNIK
 1555- 1615 (49.13/11.32)	ILKQKQLQNEITLEQYqQKIQLF.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................nQKQTELElclqsQEQQLQKQKQllhkQQSSLKSIFNI...........................
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26897 with Med24 domain of Kingdom Amoebozoa
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