<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26895

Description Choline sulfatase
SequenceMAPDLNSLPTSQSGPSASRTRKQPNILYVMADQLAAPQLKIYNEESQILTPNLDALAAKSVQFDSAYCPSPLCAPSRMSMITGRLPMAIGAYDNGAQIPSDIPTYAHYLRLKGYETVLAGKMHFVGDQLHGYENRLTSDIYPGDFGWVVNWDEPETRLEWYHNASSVEQAGVCVRSNQLDYDNEVMYRSEQFLYNHVRADPETRRPFCLTVSLTHPHDPYTIQRKYWDLYEGVDIALPKVQIPKEEQDPHSKRLLKVCDLWDKEFTPEQVKRARRAYYGAVSYVDDCLGRLLGILRDCDLEDDTIVIFSGDHGDMLGERGLWYKMSYFESSVRVPFLIHHPHDFEPHRVSQNVSTLDILPTMCDLVGARVHVDLPMDGTSLLPHLQGLAGGPDTVIAEYTGEGTVAPLMMIRRGPWKFITCPSDGVQLFNLVADPLELHDLAKSLHKKRSANGGAVLSAADADALKVLVAFETEAAARWDFDRITAQVRLSQRQRMFVWPALKIGKFTSWDHDPHDDGREKYIRSHMHLDDLERMARYPPVDRWGRVEAANMAPTMASDDTALGLTQEDLKAIDSVRGRLYQLTNSIDRLKNSVLMSNPMPTPESIQASAFVLQQNLSSLNEVMAQHAELFRRIVVHPDPMFPGRTAEQVLTSLLRKKLEPDPLGLGDIWADARAWCIDRIGDFIREEASDLYTKREREVIGIENVRTGLRRSLEEDDEDDEDEEDEDDEDEDDIATRQDQDVVMLDSIGTGTSTAPEKTEKTEKTELPRGPPVEPEVLLWLAARGDAELPRYVDIESRKAAAAKAAAAQRR
Length812
PositionHead
OrganismGrosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus) (Graphiocladiella clavigera)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Grosmannia.
Aromaticity0.08
Grand average of hydropathy-0.478
Instability index46.82
Isoelectric point4.99
Molecular weight91610.22
Publications
PubMed=21262841

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
sulfuric ester hydrolase activity	GO:0008484	IEA:InterPro
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26895
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.16|      28|      45|     694|     738|       1
---------------------------------------------------------------------------
  697-  724 (45.50/42.12)	EREVIGIENVRTGLRRSLEEDDEDDEDE
  740-  767 (41.66/10.77)	DQDVVMLDSIGTGTSTAPEKTEKTEKTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.18|      36|      45|     541|     583|       2
---------------------------------------------------------------------------
  541-  576 (60.42/45.33)	VDRW.GRVEAANMAPTMASDDTALGLTQEDLKAIDSV
  587-  623 (55.76/27.73)	IDRLkNSVLMSNPMPTPESIQASAFVLQQNLSSLNEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.81|      29|      45|     360|     392|       3
---------------------------------------------------------------------------
  360-  392 (47.69/39.96)	PTMCDLVGARVHVDLPMDGTSLLphlqGLAGGP
  407-  435 (56.12/35.64)	PLMMIRRGPWKFITCPSDGVQLF....NLVADP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.85|      26|      46|     132|     157|       4
---------------------------------------------------------------------------
   84-  110 (26.05/15.60)	...RLPMAIGAYD.NGAQIPSDIPTyahyLR
  132-  157 (50.63/38.59)	YENRLTSDIYPGD.FGWVVNWDEPE....TR
  181-  204 (34.16/23.19)	YDNEV...MYRSEqFLYNHVRADPE....TR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26895 with Med8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RTGLRRSLEEDDEDDEDEEDEDDEDEDDIATRQDQDVVMLDSIGTGTSTAPEKTEKTEKTELPRGPPVEPEVLLWL
707
782










Molecular Recognition Features






MoRF SequenceStartStop




1) PVEPEVLLWLAARGDAELPRYVDIESRKAAAAKAAAAQRR
773
812