<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26886

Description Uncharacterized protein
SequenceMHQHQQQQQHQGDAAADEVRDEMVKIAMSSTGSIDGATMDRLFGTIAMIKKEKWRHLGSGNGSTTNTTSNATDHLRLSASLFARLRRLNQTHFDTIMVKWLKRLRMLRDRPAVAIIYPVFVVFGCLDLASLLATTADEQPREPGGPVQSPARNTWRTSYLQDVLALLTAPKADRGSGSSCNATLTCDENQRFRLFLSEAPFAAPAAIAALVRNAVAEMTQWRRQQNMTTAAGHHAAPRSSVDALAVSRLLRTAAVADATAAAHALAQTTDQAVRRGLWEMTTLALTRQVVPARPALDMLRELDIFAADMGQLALGLAADGLAGLILRAVAESQLPSLHVLHSLPSDMAVSLKEHAQARFLDLVPTRKQPLRDAQHVCVATGFLDVVRTIMLSQQLQQKRQKQRPRSQPPAPPPLLLSPAIQSAAGLPALDSAVVDKLGELWCLLQEHKTSTAAAMATRQSIIQDWLPALLSLVLLHLPSRGLTTADGLGPSLPRTSRDLDQETVSAGACIVLASLCIDIVPLADDPADGNSSGRLALQTRLFDTALLLADGLSDETRQSCVRTLRDVSASVAVPNTVGAGDLSPAMAYLLSSPASASIYYPRLYLERMPAMFGRPGPQQQQQSGTSSQPTTGAVRRLAGFAAPPERSRRVRFGLKTWDAVSDPSPAVQDNDTAVNLWLLEATKVVRQRRR
Length690
PositionKinase
OrganismGrosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus) (Graphiocladiella clavigera)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes> Sordariomycetidae> Ophiostomatales> Ophiostomataceae> Grosmannia.
Aromaticity0.04
Grand average of hydropathy-0.128
Instability index56.02
Isoelectric point9.39
Molecular weight74664.64
Publications
PubMed=21262841

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP26886
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.75|      33|      37|     212|     248|       1
---------------------------------------------------------------------------
  212-  244 (60.52/32.53)	RN.AVAEMTQ.............WRRQQNMTT.AAGHHAAP.RSSVDAL
  251-  299 (36.23/11.40)	RTaAVADATAaahalaqttdqavRRGLWEMTTlALTRQVVPaRPALDML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      69.49|      17|      31|     128|     144|       2
---------------------------------------------------------------------------
  128-  144 (28.30/17.97)	LASLLA.TTADEQPREPG
  160-  177 (22.71/12.85)	LQDVLAlLTAPKADRGSG
  178-  191 (18.48/ 8.96)	SSCNAT.LTCDENQR...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     392.09|     120|     392|       1|     127|       3
---------------------------------------------------------------------------
    1-  127 (187.19/147.58)	MHQHQQQQ..QHQGDAAADEVRDEMVKiamSSTG..SIDGATMDRLfGTIAMIKKEkwrHLGSGNGSTTNTTSNATDHLR..LSASLFARLRRLNQTHF.DTIMVKWLKRLRMLRDRPAVA....IIYPVFVVFGCLD
  343-  390 (37.84/16.63)	..................................................................................LPSDMAVSLKEHAQARFlDLVPT....RKQPLRDAQHVC....VATGFLDVVRTIM
  395-  518 (167.05/111.65)	LQQKRQKQrpRSQPPAPPPLLLSPAIQ...SAAGlpALDSAVVDKL.GELWCLLQE...HKTSTAAAMATRQSIIQDWLPalLSLVLL.HLPSRGLTTA.DGLGPSLPRTSRDL.DQETVSagacIVLASL....CID
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP26886 with Med12 domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) AMFGRPGPQQQQQSGTSSQPTTGAVRRLAGF
610
640

Molecular Recognition Features

MoRF SequenceStartStop
1) IYYPRLYLE
2) LWLLEATKVVRQR
3) RVRFGLKTWD
598
676
649
606
688
658