<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26832

Description Uncharacterized protein
SequenceMDYDFKVRTSVERTKVEDLFEYEGRKIGRGTYGHVYKAKRKETFATSDINKLISADQKEYALKQIEGTGLSMSACREIALLRELKHPNVINLQRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKANKKAVYTPKAMVKSLLYQILDGIHYLHSNWILHRDLKPANILVMGEGIERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPHDKDWEDIKKMPEHPTLLKDFKRNNYQTCSLMKYMDRYKIKADTKAFHLLSKLLMMDPTKRFTSESAMADPYFQEDPLPTSDVFAGCPIPYPKREFLSDEEQDDKSDSSKQQQQQQQQRQHASQSGNSNHGHGHHPQHPSQQGNMQGGMHPNYSNHPGHPQQQSHPQQNNSFNQRF
Length449
PositionKinase
OrganismDaphnia pulex (Water flea)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.10
Grand average of hydropathy-0.745
Instability index43.35
Isoelectric point8.79
Molecular weight52239.75
Publications
PubMed=21292972

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26832
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.16|      17|      25|     393|     417|       1
---------------------------------------------------------------------------
  400-  417 (34.60/26.68)	N.SNH.GHGHHPQHPsQQGN
  425-  443 (28.56/ 7.29)	NySNHpGHPQQQSHP.QQNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.79|      16|      26|     250|     267|       2
---------------------------------------------------------------------------
  250-  267 (22.23/18.10)	EDIKtSNPyHHDQLDRIF
  279-  294 (30.56/14.88)	EDIK.KMP.EHPTLLKDF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.29|      10|      16|     344|     355|       3
---------------------------------------------------------------------------
  344-  355 (15.92/14.66)	PYFQEDPLptSD
  363-  372 (20.37/10.70)	PYPKREFL..SD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26832 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IPYPKREFLSDEEQDDKSDSSKQQQQQQQQRQHASQSGNSNHGHGHHPQHPSQQGNMQGGMHPNYSNHPGHPQQQSHPQQNNSFNQRF
362
449










Molecular Recognition Features






MoRF SequenceStartStop




1) QQQQQQQRQHASQS
385
398