<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26816

Description Uncharacterized protein
SequenceMQQQPSPPHSPSQIKEKLLQALDRDYHVVDMALALEAVSLLEKTPVTKEALETTRLGRLVNEMRKKTKNDSLARRAKDLVRRWRDMVSKPSENGTGGTGQGPGASLVNHLRVAGVKNSVSSPALCEMGRTASPALPRPVHNLAISPTSPAFRGVTLSPALQRKSSQSTGGLQLQQQRVISPSNSVASNTSTSPGLSFSLSQTHSNSSRPSTPSSLVVKSKAISPGPGRPMIDSSEFPSKTNHHRGIKRTRDNDEETMTGFELTGKRSRGSNGVDWPWMDECSRDSNLSWSGDSLRMTNHSALGGGEDRSISSSSKASRPPRGRSKVEVNVKPEPTSDVLREKFASIARVSKVKTTQELLEDLARRSGSPNLIVKPEIHSVHQQQHQQQPLTVPPSNEARQWPDAKQEILDKFFRSHSTDRRSDGITTTSSVVSKPKTTATPAINDPVAEIYARLPPLDPAVVASLWKEEVKPETEELETDSSVPERPVTDEDVDLLHNGSVDDVNGSRDINGEFHQWHETVTVASYHGDPLHLLPYVVIE
Length540
PositionUnknown
OrganismDaphnia pulex (Water flea)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.04
Grand average of hydropathy-0.709
Instability index62.43
Isoelectric point8.85
Molecular weight59072.29
Publications
PubMed=21292972

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26816
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     477.06|      99|     124|     262|     360|       1
---------------------------------------------------------------------------
   83-  172 (97.57/40.35)	...............WRDMVSKPSengtGG.TGQGPGASLVNHLRVAGVKN.SVSSPAlcemgRTASPalPR...PV.H.NLAISPTSPAFRGVTLSPALQRKSSQSTGGLQ
  173-  242 (90.72/37.04)	LQQQRVISPSN...SVASNTSTSP....GL.SF...SLSQTHSNSSRPSTPSSLVVKS.....KAISP..GPGRPMI.DSSEFPSKTNH.......................
  262-  360 (163.65/72.28)	LTGKRSRGSNGVDWPWMDECSRDS....NL.SWSGDSLRMTNHSALGGGEDRSISSSS.....KASRP..PRGRSKV.EVNVKPEPTSDVLREKFASIARVSKVKTTQELLE
  390-  478 (125.12/53.66)	LTVPPS..NEARQWPDAKQEILDK....FFrSHSTD..RRSD....GITTTSSVVSKP.....KTTAT..PAINDPVaEIYARLPPLDPAV...VASLWK.EEVKPETEELE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26816 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NLSWSGDSLRMTNHSALGGGEDRSISSSSKASRPPRGRSKVEVNVKPEPTSDVLREKFASI
2) SPALCEMGRTASPALPRPVHNLAISPTSPAFRGVTLSPALQRKSSQSTGGLQLQQQRVISPSNSVASNTSTSPGLSFSLSQTHSNSSRPSTPSSLVVKSKAISPGPGRPMIDSSEFPSKTNHHRGIKRTRDNDEETMTGFELTGKRSRG
3) TTQELLEDLARRSGSPNLIVKPEIHSVHQQQHQQQPLTVPPSNEARQWPDAKQEILDKFFRSHSTDRRSDGITTTSSVVSKPKTTATPAINDPVAEI
4) VASLWKEEVKPETEELETDSSVPERPVTDEDVDLLHNGSVD
5) VTKEALETTRLGRLVNEMRKKTKNDSLARRAKDLVRRWRDMVSKPSENGTGGTGQGPGASLVNHLRV
286
121
354
462
46
346
269
450
502
112










Molecular Recognition Features






MoRF SequenceStartStop




1) LVRRWR
2) VAEIYARL
3) WPDAKQEILDKFFRS
79
447
401
84
454
415