<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26810

Description Intersex-like protein
SequenceMAMHMTGMSNQGMMNLTPLQQQQLLQQQQQQQQQQQAAANNPQQMLQHQQQSQPVPNQQAAANPNMPNPAAPNPAAEQQKLDHIAKVKTLLWPLKESLIASFKTAAQNFNQNGMIDFGTMKGTETNVPRFDKQLEEFYSICDQIELNLQAAIGCASQISTSQRHVPSQVSIARQEPVINQEIMSYPNYVGVAKTQVAYVKDVIDTLNDAAQNLSND
Length216
PositionTail
OrganismDaphnia pulex (Water flea)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.05
Grand average of hydropathy-0.622
Instability index64.89
Isoelectric point5.50
Molecular weight24013.76
Publications
PubMed=21292972

Function

Annotated function
ECO:0000256	RuleBase:RU364147
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central
transcription factor binding	GO:0008134	IBA:GO_Central
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP26810
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.59|      20|      20|      23|      42|       1
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   23-   42 (39.66/15.91)	QLLQQQQQQQQ..QQQAAAN....NP
   44-   69 (30.94/10.90)	QMLQHQQQSQPvpNQQAAANpnmpNP
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP26810 with Med29 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MAMHMTGMSNQGMMNLTPLQQQQLLQQQQQQQQQQQAAANNPQQMLQHQQQSQPVPNQQAAANPNMPNPAAPNPAAEQQK
1
80

Molecular Recognition Features

MoRF SequenceStartStop
NANANA