<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26801

Description Uncharacterized protein
SequenceMALDGSKVQALVSEALKVDAIEEAFNDFLIQRKDEGIKYSALEKDLIAMMNDSQAESQDAILPQFIAVISGVSSDSHSKILFKLLESVVNTNIATSRKVCDSLLGNEKLTPANPLLWQGSFSLIRKIVCHVDYKGVREIMKTCLEKAQLLPSRFSTSEYPNVTALEHTLKHILDRQVCLLPAYFIVNEIRKMYPENKDWPHWKLAGLLSEVVDSFRPLVQMLSPIGRPLMFPVVDPSAHGVHHSWKLEQGTLKLALKGNLPYEKEYTEPQTRLIRYVLEQPYSREVLCGMLGLQKQHKQRHAVLEEQLVELLVQAMERAEIAPEQDSDAADELGVSHWLWHHLSSQIIYFVLFQFASFSHLVTLLHEKLAERKLRKGRDQLMWVLLQYISGSIQKNPLAEFLPLLRLYDLLYPEREPLPVPDYTRPICVHQMAVACIWIHIVKKAQTEQQKLQRHFPQALKNHQEFLQHNALNPPSSAPSGDYRVALLCNAFSTTLDCLARPMGSLMESLHGNLSQKGSGNAGGSAGGMPNTGPISPIPLAFLDALTVHAKMSLIHSIVTHVIKCAQTKMNVPLAPALVETYSRLLVYTEIESLGIKGFITQVMTSVSKSQAWGIFHTLVEMFTFRVHHMQPQYRIQLLTLLHSCAVPQQHQTQLILCVENAALRLIGLLGAAEMQPCYSRSAADIKPLFSSDSEELNRALILTLARVISVAGCETQHSSWYKDLLTLIQQQTPHSWSSNTRDCFPPPLAEFFGQAANQPVKESKQQLKQNIEEEHRKVLTMNPDDWPAHFAPQSNNPPFFLCLLWKQLLETERINPVAYKCIERIGARGLGSHLRTFCDFLVYEFANSGKGQHVNKCIDVLNEMVWQYNVVTIERLVLCLALRPLEGNEAQVCCFIIQLLLLKTPQFRSRVQDFVKDNSSEHWRQNNWHEKHLAFQRKFPERFGPPESVLESIGQGGSYQSLPTYFGNVCLRFLPVFDITIHRFTEIPPVTKSLETILEHLGCLYKFHDRPVTYLYTTLHYYERKLRDRPLLKRKLVSSIMGSLKDVRPPGWALSESYLNYSTRQADDLNWLPELDYYVKLVGRLVDTTAGRSPFPFPAMDWRFNEFPNASCHALYVTAVELLALPASPAIVANALMDVVLQGYNLLPVSEETPLESWVNAVGLLLTYLPESYWSVLYDRIVELLSGPQLSTYTYPCSPLHLFHFSTVVGQGLDAPFVLLLAVSHAFFTHANIGQMGGLPQFVKDRLHPLIRTEEQYLWLCHLIGPTLQRFSVDKPKCVFDLTVELYELLEQVDKNVAEIRMIDPICDLLYHIKYMFTGDQVKTEVEQVIRNLKPPLRLRLRFISHLNPQ
Length1351
PositionTail
OrganismDaphnia pulex (Water flea)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.09
Grand average of hydropathy-0.090
Instability index45.57
Isoelectric point6.77
Molecular weight153806.31
Publications
PubMed=21292972

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26801
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.05|      15|      37|     746|     760|       1
---------------------------------------------------------------------------
  746-  760 (28.62/13.14)	PPPLAEFFGQAANQP
  784-  798 (31.43/15.07)	PDDWPAHFAPQSNNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.65|      30|      37|      82|     111|       2
---------------------------------------------------------------------------
   82-  111 (48.12/33.18)	FKLLESVV.NTNIATSRKVCDSLLGNEKLTP
  121-  151 (45.53/30.99)	FSLIRKIVcHVDYKGVREIMKTCLEKAQLLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.05|      37|      42|     546|     582|       3
---------------------------------------------------------------------------
  546-  582 (62.41/47.81)	LTVHAKM.SL.IHSIVTHVIKCAQTKMNVPLAPALVETY
  585-  623 (53.64/39.93)	LLVYTEIeSLgIKGFITQVMTSVSKSQAWGIFHTLVEMF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.83|      15|      42|     194|     208|       4
---------------------------------------------------------------------------
  194-  208 (31.79/16.92)	PENKDWPH.WKL.AGLL
  236-  252 (22.03/ 9.60)	PSAHGVHHsWKLeQGTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     398.20|     133|     873|     276|     474|       5
---------------------------------------------------------------------------
  320-  474 (203.29/264.28)	EIAPEQDSdaadelgvSHWLWHHLSsqiiyfVLFQFASfsHLVTLLHEKLA..ERKLRkGRDQLMWVLLQYISGSIQKNPLAEFlPLLRLYDLLYPEREP.....LPVPDYTRPICvhQMAVACIWIHIVKKAQTEQQKLQRHFPQALKNHQEFLQHnaLNP
  987- 1078 (117.16/63.02)	EIPPVTKS........LETILEHLG......CLYKFHD..RPVTYLYTTLHyyERKLR.DRPLLKRKLVSSIMGSLKDVRPPGW.ALSESY.LNYSTRQAddlnwLPELDY...................................................
 1286- 1350 (77.76/31.37)	........................................................................................ELYELLEQVDKN.....VAEIRMIDPIC..DLLYHIKYMFTGDQVKTEVEQVIRNLKPPLRLRLRFISH..LNP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.20|      17|     148|     479|     502|      10
---------------------------------------------------------------------------
  479-  502 (21.88/30.70)	PsgDYRVALLcnafsTTLDCLARP
  632-  648 (33.32/19.49)	P..QYRIQLL.....TLLHSCAVP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26801 with Med23 domain of Kingdom Metazoa
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