<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26799

Description Uncharacterized protein
SequenceMTSPFRNPQNESTAVITIGGDTPDTGKESSPTKFKVHENQPTLNSNSTPTRMFLRRRIVLLTLALILAIVIITVTIVGLLISSYNDRQQAEAEARKDQGTHMEIEKYEEMEKKMSSIASDLPESDDTEMDERDFLPVPPATTNTDSSGSGFEPSSTEKTSVNVNSVPLTDEYESSQEVGSGDSLDHHQASSGDNSEDRHFDMGSGDFSGDRRDVGSGFEHNQPVIKLEISVIERMTESVEQKLKHLMRKAWRERWTDLMWGIYVKEVIPAGSTGDTYNLAESILQQALIGPSPNSKLLSYLQHSLHVQIVSYSAVFENICLQGSIQKTRCLLELLLLVEQSIKHISCTGSGDGPAALAASLLSLETWLWSLTSDGLKNLFDNNSATNDYSVICHYTTGLLGTLYEENYLISLLYIARCCTNDQFSATQLTSLVNQTESNLKNLTTNGNPSSEKLVESVEKVMRQCRSFENDLFKENGPEKPFYENSLCTDVHTLISWEALLRPTSDGLELTRQLEVLQKLRGYSPTQLYCEILRACCLGLAETADSPGELRWAVFTFLKAPSLLLRLHRSIFGLDPNSPIGEPSPEVAGAFERLLCYPGLLETTDAKCHCNVVEGLLNEVKIRTSLLSEWHVTSILSKRESLSRGGLKLETTNTQIATLVLRAEPTVASILKTLDTDYAKNQDTLLKVLSHLLSGQSFELILNAATGTGKLRAFATKLVRFNEANRQPAGSDPSKTANARALLFDISFLMLCRITQMYGIEVILSGELGGETFFEQWASEWLKPNQAPDLSLSRCDPMLTDQLLKALTSGESDLRSGSVRWHEACFHVPAVIREILGAYESQLVSDEEVERILDTLRTQMCCLSVCAAAWLRFYIQVQPANLKSKPTSMLDHLMTSLNLDDSKEHYRERSVLMLQIIRRLAQDDNPLQSVSENHDQSLDHQLTKLWNKILNHGWSDHSTTVGIDQLFKIGGATWLVTSLVKAVIKEQSSDKRQRCVEGALSVAHLDLESCAISLATRVLPFLLTHSSMLASDEETGGPGGKALAQLTVLLFTAALNNQLAPESDSSSPSKKLGSKRSIDWDLNTPGFRYPPLKKMALHEEEFDFMFVTPNSAHENNPLSNAIANLMQLMTRAAGEGIITPQLAFISYFIQTMAEITSIKTKEVMRPLLTLIPPALVFYMLAVWPGLMSISDVAKLLAHPGDEMGVGKIAAQIVCAFKNIN
Length1220
PositionTail
OrganismDaphnia pulex (Water flea)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Crustacea> Branchiopoda> Diplostraca> Cladocera> Anomopoda> Daphniidae> Daphnia.
Aromaticity0.06
Grand average of hydropathy-0.187
Instability index44.52
Isoelectric point5.28
Molecular weight135098.22
Publications
PubMed=21292972

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26799
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.96|      21|     131|     357|     377|       1
---------------------------------------------------------------------------
  357-  377 (37.17/22.45)	LAASLLSLETW..LWSLTSDGLK
  487-  509 (34.79/20.50)	LCTDVHTLISWeaLLRPTSDGLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     392.72|     131|     150|     692|     841|       2
---------------------------------------------------------------------------
  692-  813 (157.70/143.38)	.............................................................LLSGQSFELILNA.ATGT..GKLRAFATKLVRFNEA.NRQPAG.SDPSKTANARALLfdiSFLMLCRITQMYGIEVILSGELGGEtffeqwasewLKPNQAPDLSLSRC.DPMLTDQLLK....ALTSGESD
  814-  956 (193.86/158.56)	LRSGSVRWHEACFhVPAVIREilgayES................................qLVSDEEVERILDTlRTQM..CCLSVCAAAWLRF.YI.QVQPAN.LKSKPTSMLDHLM...TSLNLDDSKEHYRERSVLMLQIIRR..........LAQDDNPLQSVSENhDQSLDHQLTKlwnkILNHGWSD
  967- 1066 (41.15/18.81)	FKIGGATWLVTSL.VKAVIKE.....QSsdkrqrcvegalsvahldlescaislatrvlpfLLTHSSM.LASDE.ETGGpgGKALAQLTVLL.FTAAlNNQLAPeSDSS....................................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.97|      13|      15|     122|     134|       3
---------------------------------------------------------------------------
  122-  134 (23.41/15.10)	PESDDTEMDERDF
  139-  151 (22.55/14.24)	PATTNTDSSGSGF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.93|      20|     584|     588|     607|      11
---------------------------------------------------------------------------
  588-  607 (36.82/22.15)	AGAFERLLCYPGLLETTD.AK
 1174- 1194 (33.11/19.18)	ALVFYMLAVWPGLMSISDvAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.65|      30|     228|     427|     456|      14
---------------------------------------------------------------------------
  427-  456 (49.26/31.01)	TQLTSLVNQTE....SNLKNLTTNGNPSSEKLVE
  654-  687 (42.38/25.68)	TQIATLVLRAEptvaSILKTLDTDYAKNQDTLLK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26799 with Med24 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MTSPFRNPQNESTAVITIGGDTPDTGKESSPTKFKVHENQPTLNSNSTP
2) RQQAEAEARKDQGTHMEIEKYEEMEKKMSSIASDLPESDDTEMDERDFLPVPPATTNTDSSGSGFEPSSTEKTSVNVNSVPLTDEYESSQEVGSGDSLDHHQASSGDNSEDRHFDMGSGDFSGDRRDVG
1
87
49
215










Molecular Recognition Features






MoRF SequenceStartStop




NANANA