<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26794
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MAPVDRLDQDVLEQQLKDVIQDLYQIMVQVSTYDTTGRPSRDVLSNEMKTLSASLQALHATTSGNASLPSVPPELLEYVENGRNPDIYTREFVELVRRGNQLMRGKMHAFGEFRDVLAREMATALPELRPDVERVVRETGGRPLPEVNGDTAAASSSTGAPGNGTR |
Length | 166 |
Position | Middle |
Organism | Metarhizium robertsii (strain ARSEF 23 / ATCC MYA-3075) (Metarhizium anisopliae (strain ARSEF 23)) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Hypocreales> Clavicipitaceae> Metarhizium.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.498 |
Instability index | 37.24 |
Isoelectric point | 4.98 |
Molecular weight | 18267.29 |
Publications | PubMed=21253567
PubMed=25368161
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26794
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 45.84| 14| 15| 69| 82| 1
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69- 82 (25.65/14.88) PSV.PPELLEYVENG
85- 99 (20.19/10.55) PDIyTREFVELVRRG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 74.84| 23| 102| 9| 57| 2
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34- 57 (36.13/58.37) DTTGRPSRDVlSNEMKTLSASLQA
138- 160 (38.71/12.05) ETGGRPLPEV.NGDTAAASSSTGA
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