<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26748
Description |
Mediator of RNA polymerase II transcription subunit 31 |
Sequence | MAQEAGLVPPPPHLSNPRFTLELEFVLSLANPYYISHLAVTYPHLLGISSQSTDNDDPSASSDAKAFAAYLAYLYDYWKRPEYVQFLTHPGATLRALRLLQEESFRKAVIRPQVIEALLGTTTEVVLHVESEEDREKNNEEQAEKGSNGATS |
Length | 152 |
Position | Middle |
Organism | Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Onygenales> Onygenales incertae sedis> Coccidioides.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.380 |
Instability index | 50.61 |
Isoelectric point | 4.94 |
Molecular weight | 16961.72 |
Publications | PubMed=20516208
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription, DNA-templated GO:0006355 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26748
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 38.18| 12| 30| 80| 93| 2
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80- 93 (17.42/17.38) RPEYVQFLThpGAT
111- 122 (20.76/11.87) RPQVIEALL..GTT
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|