<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26711

Description Uncharacterized protein
SequenceMPVTQRHPAGINPWRTLARRPGGPSSITASTLASTASYAWDRAYSVAGYPDFYPSRPGFDQPEDVLTEENVKSGFAGKPFVSEVVRTLCQLGMQSAYMSTGRDVLDAWTYTPASVWRMSQYAHAAGQGPCREARGIYAAVPLTCANRERSFRIPGRVIYTDNKRLGFLADLGNPDIPLHWLMRNQIPHGFKGVELLDVMFSPLATVRQPPPNLAPMDPIPIDRAIWLIRVIGSNDIAAHRARQHQTATSVPAPSPAAATPSSTTTVTATPALPVSSNDWYSQEFTNTVISWLRIQLGQLALPNTVKVAGKLPVAKAGSGILQDEKARAKWLAKWDYSTRLLRALHTKHLISTRLFTGWLADHLTHVNLAQLGFLAQLIGEYLDDLVHHLGSARHCLRAACDKLVEVRNSPGKELLQKVETMLTTIIQVLYEANPDVLLSPSTWKLHSPLLAAILPSSSPQWENLKRRNEALTFKPTVSAGSSNPRRQHMAEIQKLDSICEDTDMRQLTFMFFDGAASPTCSPVDLVKFEEKVFTLLNWSMGLYQLGAHRPYAVYTLLKHWHEQQEEHQQAAASHAKQRQHIDLFEVVYKWLDTAPAARNQDNVRAIGITIGELTRRGMFSYGRYLQTLIANGQTARNLRSPSDKRSHHLALLESMPIFVMAKDLFQQRRIALSGDDLEVRRRDELEEQGVLAAFEERVKEYVPEVYGLKSHGQSEALKTMVHYEIPTSSQLTRYLYVYARFSIAAHAGAMLKSDGKRPAMDASTFARVTQVFRQSHGYATIADFMIRALQEAEDDEILDVILDIIKRDADVWTAMDLWPRLGDKLLDRHHVLERKGKEHPRLMQLLRVLAQKKRLTPDDEDEVEQLQTSIDKSTTPPGGIKLVDIFEVLPHILTTGKESKAISVAPALFRQCGSFSSWSLKWWMLILDVVQKANTEQKPFLYHAISTHLSAVLGQHGDTLDDAVTSWLENLSAVSLVETFGKRSSGVLIRLLLFLVSHRFLSTWVLLEKAVFPIWKHASPFALPPRKRLSSKQIQAITSTVNIIAQLLISPPLIPDFPPVSLKESLIVQASRQPVLQRLSVGILIQHLPLLVVFEQSKLLPDQISQRIDAILRNLAMTAEFKTAAFRNLNLLKDAFLAREWSGPGMDQGLEGKMIDVLKRIMSEKPTQPSPKQGLPNFDTSARFSAWRWTRVVLEMRVEFKALTMRIAEGQNVAEAKQTLNQLVHATLDRETTADDTDLLCEVFRGVDSMVTQEILAAGLERLATLLGHAIAAESQQQLETNIKSIDQLLRILDSMNNLPSQSVTEASVLNARHKLLDLLALALQTVERNLSTTRDGSDLLLPPGISPPQPSHLLKAVMGLLKFTLGSVGSENGSLAAPKPNFPHLAVCFLKAIFASDGILDSSSAKIMADMLVYIIDCTSPQARLICQSALLAETASPHAQSILSSFPELSAALPYLSPVQRHMSLVTPDTADHISDSALPLDDRHWELFEYIGPPKRKIGPQDLFLASTPLKDASSIPITLFDPKITRDAPPNAGTMDAYDKAAENGEMSPTVNSASPVGEEEEPRRSWETFASERNLGDGLAGEPAYAKQAATLVFSARDNDVPEVMPVKSTASQQPVVVVPSSTSPQKPKGKRSNSSGKDKATGSNKDAPIAVEEDENDEDSEVEAPLSKKAKTAKNSAAGSGKSTTTAGKAPARKTTGGKGVSKKATGKSAKESGTGKAKGGRRKSQAE
Length1734
PositionKinase
OrganismCryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) (Filobasidiella gattii) (Cryptococcus bacillisporus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Tremellomycetes> Tremellales> Cryptococcaceae> Cryptococcus> Cryptococcus gattii species complex.
Aromaticity0.07
Grand average of hydropathy-0.245
Instability index47.73
Isoelectric point8.59
Molecular weight191283.63
Publications
PubMed=21304167

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26711
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.58|      16|      19|    1694|    1710|       1
---------------------------------------------------------------------------
 1679- 1697 (19.82/ 9.19)	AKNSAAGSGKSTttaGKAP
 1698- 1716 (20.76/11.90)	ARKTTGGKGVSKkatGKSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     159.45|      52|     241|     363|     417|       4
---------------------------------------------------------------------------
  363-  417 (80.41/50.27)	LTHVNLAQLGFLAqlIGEYLDDLVHHLGSARHcLRAACDK....LVEVRNSP....GKELLQK
  608-  667 (79.04/40.18)	ITIGELTRRGMFS..YGRYLQTLIANGQTARN.LRSPSDKrshhLALLESMPifvmAKDLFQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     269.95|      96|     201|    1068|    1178|       5
---------------------------------------------------------------------------
 1061- 1105 (47.64/42.78)	....................................................SLKESL..IVQ.ASRQPVLQRLSVGILIQHLPLLVVFEQSK.LLPDQIS
 1118- 1183 (81.25/62.60)	TAEFKTAAFRNLNLLKDAFLAREwSGPGMDQGLegKMIDVLKRIMSEKPTQPSPKQGLPNFDT.SAR..................................
 1252- 1347 (141.06/92.65)	TQEILAAGLERLATLLGHAIAAE.SQQQLETNI..KSIDQLLRILDSMNNLPS..QSVTEASVlNARHKLLDLLALALQTVERNLSTTRDGSDlLLPPGIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.65|      23|     242|     197|     226|       6
---------------------------------------------------------------------------
  199-  224 (37.25/36.98)	MFSPLATvRQPPPNLAPMDpiPIDRA
 1523- 1545 (44.40/17.56)	LFDPKIT.RDAPPNAGTMD..AYDKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.05|      25|     242|      18|      45|       7
---------------------------------------------------------------------------
   18-   45 (39.58/31.76)	ARRPGGPSSITASTLASTASYAWdraYS
  257-  281 (44.46/27.16)	AATPSSTTTVTATPALPVSSNDW...YS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.84|      15|      15|     826|     840|      10
---------------------------------------------------------------------------
  826-  840 (26.71/14.49)	LDRHHVLERKGKEHP
  843-  857 (24.13/12.45)	MQLLRVLAQKKRLTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.47|      16|      17|     455|     470|      14
---------------------------------------------------------------------------
  455-  470 (29.53/18.19)	PSSSPQWENLKRRNEA
  475-  490 (28.94/17.67)	PTVSAGSSNPRRQHMA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26711 with Med12 domain of Kingdom Fungi
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