<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26687
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MNTAGSNAYAAAIITVEMQLKDIVQNLYNLIVQSYDHHGGKTQEAMKREIQSLVQNLVKLSSTAPSVQIDIPPEVTTYVENSRNPDIFTREFVETVQRMNQMLNGRVDAYRMLQDQLARQISSVIPELKDDVNAVLQSTGGNVLA |
Length | 145 |
Position | Middle |
Organism | Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Pleosporineae> Leptosphaeriaceae>
Leptosphaeria> Leptosphaeria maculans species complex.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.263 |
Instability index | 34.58 |
Isoelectric point | 5.08 |
Molecular weight | 16165.15 |
Publications | PubMed=21326234
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi
mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | negative regulation of transcription by RNA polymerase II GO:0000122 IEA:EnsemblFungi
positive regulation of transcription by RNA polymerase II GO:0045944 IEA:EnsemblFungi
RNA polymerase II preinitiation complex assembly GO:0051123 IEA:EnsemblFungi
|
Interaction
Repeat regions
Repeats |
>MDP26687
No repeats found
No repeats found
|