<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26681
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MSTEEPTQPSPMDTATTTTTTSSSSSSSTAPPPQPSAQQDASQPTSQPETYRQVAAAHIATLSEINHQLPKMLRYFATALTQLTDHPIHDTHNTNNNDNNTNTQPTDTLESRREAFRKYATFTGMSVNLIREELVRQIEDLEAYKVIPTSHPKFTVAKRHGDTAPSKEETDPQAGVRNGGYGDFDVGVLNARASTGLGGEDVLERVRGVLEELARRSGGNEGVDGVKDEQMVGVDG |
Length | 236 |
Position | Head |
Organism | Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Dothideomycetes>
Pleosporomycetidae> Pleosporales> Pleosporineae> Leptosphaeriaceae>
Leptosphaeria> Leptosphaeria maculans species complex.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.802 |
Instability index | 57.08 |
Isoelectric point | 4.99 |
Molecular weight | 25565.58 |
Publications | PubMed=21326234
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26681
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 68.19| 18| 24| 2| 19| 1
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2- 19 (33.52/15.19) STEEPTQPSPMDTATTTT
28- 45 (34.67/15.92) STAPPPQPSAQQDASQPT
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