<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26613
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MASGSSMPFSSLHPVPTGGRKPKSLGEFIARVQSERGFRNVTEESLKEEVENQKNGDAEVKDEDTAMSDGNADDEEPPDAGAARMEVLRNIDVAQNAALMTLDFISLLLSKESPAQAGVTLSQALRDWTGIGTLGIAKREDSEEQKQRDADRAKDNRDVSLGWALLDIQTTKESADKAASHLSKEVEREAKYWDQVLAVHRAGWSMCRLPAERHTLGVRFGFSEASPEFRNSSLAPLRRGDDGTALLQHGRVGAGSQRLSITVSRSGETTGRLAIGSSVPDSAHLPDRVLEARNTIFAQELWHELHREAHSLASYGVRANNDSITFNPASGPSLTLELETLDGGAPAVGASTEDNVLAEATHLGLHILLSHAHRLNELQRLRPTPPHQRRNQTQSQYHLLRPIVAKILYDRSVEQVTSFAGDLTRVLRRAGVHAASFTLSTPPFPTADLKNTSGGASNRPNASQALTNMLTSPADFQVELTLTPTARLQIRGRTFLLPLTTTQFQLQLLPSIAEPTSAEPASSSLQASYPPSRDPYPDFPSVQRYVASAAAHALTDFAMSFIPATPANLSEPAHGEWSKSVRGTAIRDMDTETREIRFDVLSNDHEGRLTLQIGAAWRAGDKPLVKRWAWPAVGEGAGKSATQPHVGEIVAAVVQSKEI |
Length | 659 |
Position | Head |
Organism | Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Glomerellales> Glomerellaceae> Colletotrichum>
Colletotrichum graminicola species complex.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.451 |
Instability index | 44.74 |
Isoelectric point | 5.96 |
Molecular weight | 71555.02 |
Publications | PubMed=22885923
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26613
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
6| 338.13| 57| 57| 410| 466| 1
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242- 286 (46.14/17.74) .............DGT.A..LLQHGRVGA.GS...........Q..RLSITVSRSGETTGRLAIGSS.......VPDSAHLP
287- 352 (54.33/22.07) DRVLEaRNTIFAQELW.H..ELHREAHSL.ASygvranndsitF..NPASGPSLTLELETLDGGAPA.......VGAST...
354- 408 (39.97/14.47) ....D.NVLAEATHLG.LhiLLSHA..HR.LN...........E..LQRLRPTPPHQRRNQT.....qsqyhllRPIVAKIL
410- 466 (87.23/39.50) DRSVE.QVTSFAGDLT.R..VLRRAGVHA.AS...........F..TLSTPPFPTADLKNTSGGASN.......RPNASQAL
468- 525 (60.25/25.21) N.MLT.SPADFQVELTlT..PTARLQIRG.RT...........FllPLTTTQFQLQLLPSIAEPTSA.......EP.ASSSL
530- 575 (50.21/19.89) PPSRD.PYPDFPS.VQ.R..YVASAAAHAlTD...........F..AMSFIPATPANLSEPAHG..................
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 53.17| 18| 24| 134| 153| 3
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134- 153 (21.88/23.36) LGIAkREDSEEQKQrDADRA
161- 178 (31.29/20.79) LGWA.LLDIQTTKE.SADKA
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 34.77| 10| 16| 57| 66| 5
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57- 66 (16.53/ 8.34) DAEVKDEDTA
74- 83 (18.24/ 9.95) DEEPPDAGAA
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