<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26592

Description CRE-CDK-8 protein
SequenceMIDENFKKRLAVSRERVEDLFYFENSKEIGRGTYGLVYKAVPKHPNGRFPNKEYALKMIEGQGFSMSACREIALFRELRHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKTKKVPIMVPRNMVKNILFQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIFHLLGYPSDTDWPDMKKMPDHARLLNDARNEGTPIQTFPNSLQRYFDKWKINSQSSPYRLLVKLLTVDPTKRVSCEEAMNDIYFRKMKRPPRETDDVFNKYPIPYAKKEQQMTVPIDHVQQQQQQQQQQQQQQQQQQQQQQVQMQQPQMGPPQMMGQPQMVQPQMVQNQMGPPQMGQPQMGQPPMGGPHPGVVPQDPHAHQMMQQQHHMQYQQMHDPMQGGMDEGPQAKMMRMGNVPVPRYGPMPPPYGGPQDYHNQQGPPMMQMMQQPGPSGYYGQRPGQPQVPGPGPQGYMNPQMGMQMGMRPPGVPPQAYMQQGRGMPPQMGQPGPSQQQQWQQYHR
Length601
PositionKinase
OrganismCaenorhabditis remanei (Caenorhabditis vulgaris)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.09
Grand average of hydropathy-0.817
Instability index60.00
Isoelectric point9.33
Molecular weight69635.66
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26592
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.91|      17|      18|     409|     426|       1
---------------------------------------------------------------------------
  405-  425 (32.98/10.98)	MqqpQMGPPQmMGQPQMVQPQ
  426-  445 (36.92/ 9.67)	MvqnQMGPPQ.MGQPQMGQPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     147.29|      21|      35|     508|     528|       4
---------------------------------------------------------------------------
  447-  465 (31.69/ 7.73)	..GGPHPGVVPQDPHA.HQM.MQ
  508-  528 (48.95/16.02)	PYGGPQDYHNQQGPPM.MQM.MQ
  546-  565 (31.07/ 7.43)	PGPGPQGYMN...PQMgMQMgMR
  578-  597 (35.58/ 9.59)	GRGMPPQM.GQPGPSQ.QQQ.WQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.05|      10|      35|     306|     320|       5
---------------------------------------------------------------------------
  306-  320 (16.86/20.40)	YFDKWKinsqsSPYR
  344-  353 (21.19/11.08)	YFRKMK.....RPPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.72|      17|      37|     115|     131|       7
---------------------------------------------------------------------------
  115-  131 (31.15/16.00)	HRTAKTKKVPIM..VPRNM
  153-  171 (27.57/13.40)	HRDLKPANILLMgdGPPDM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26592 with CDK8 domain of Kingdom Metazoa
Unable to open file!