<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26577

Description Uncharacterized protein
SequenceMAANYWLSSHANSHILTRHDLRNSPGRSIDLKYAGEREMACINIWSSNVIHKIGKRLNCRQIVTATAVTYFRRFYVKNAIAETDPCLVAAAAVYVATKVEEAPSHIKTVLEAARSVFSDYPALGPFPNDATVLAEMEFYLIEDLDFHLIVWHPYRDLAQFAGREDSAVPKDAMERMSEWTPGPNSPLYQEYRKECDRQASMLDLSDTTLQMAWFIINDTYRTDLILLYPPYIIALAAIYITVVIHPHPAMKTLPQATKPTRRSSDETGPSSRTRRQSMNPSTPLANLPGRVEGTTGTGTALPASPSTPTKVVPLDFFARFPISMSLVLELVQEIVASYELWNRLENPSLSIHRPPEDPEKIPRGLASTRLNRPIYSPDSSSSIPSSSAANPSTSASHSHQSASSSPVTTKASGDKAADERVVDILLRMHKARELDQSA
Length438
PositionKinase
OrganismPuccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL) (Black stem rust fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina> Pucciniomycetes> Pucciniales> Pucciniaceae> Puccinia.
Aromaticity0.08
Grand average of hydropathy-0.309
Instability index59.72
Isoelectric point6.68
Molecular weight48605.55
Publications
PubMed=21536894

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IBA:GO_Central

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26577
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     125.80|      35|     124|     153|     187|       1
---------------------------------------------------------------------------
  153-  187 (64.75/34.63)	PYRDLAQFAGREDSAVPKDAMERMSEWTPGPNSPL
  280-  314 (61.05/32.28)	PSTPLANLPGRVEGTTGTGTALPASPSTPTKVVPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     219.24|      69|     142|      56|     125|       2
---------------------------------------------------------------------------
   56-  125 (111.50/77.84)	RLNC.RQ..IVTATAVTYFRRFYVKNAIAETD......PCLVAAAAVYVATKVEEAPShIKTVLEAARSVFSDYPALGP
  192-  269 (107.74/70.19)	RKECdRQasMLDLSDTTLQMAWFIINDTYRTDlillypPYIIALAAIYITVVIHPHPA.MKTLPQATKPTRRSSDETGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.74|      16|      23|     343|     362|       3
---------------------------------------------------------------------------
  343-  362 (24.59/25.01)	RLENPSLSihrpPEDPEKIP
  369-  384 (30.15/17.62)	RLNRPIYS....PDSSSSIP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26577 with CycC domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ENPSLSIHRPPEDPEKIPRGLASTRLNRPIYSPDSSSSIPSSSAANPSTSASHSHQSASSSPVTTKASGDKA
2) KTLPQATKPTRRSSDETGPSSRTRRQSMNPSTPLANLPGRVEGTTGTGTALPASP
345
251
416
305










Molecular Recognition Features






MoRF SequenceStartStop




1) KAADERVVDILLRMHKARELDQS
415
437