<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26572
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MSPPSTNSPGVPQSTPGFQSEYSTAEEVHRAHLEDKLEQLLQSLLEVGICTSNVQENAREGGRTGRGEPLGPGGLVGKKINESIGHMAELYELNANIASEIPIPLEVITQVDQGANPDRWLKSFVERAAHENMYTNGILSNINQYRTLLQNKLADHFPELHQQLNQNQNQNSTSTPPDKSDNPPANSTQV |
Length | 190 |
Position | Middle |
Organism | Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL) (Black stem rust fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Pucciniomycotina>
Pucciniomycetes> Pucciniales> Pucciniaceae> Puccinia.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.754 |
Instability index | 43.77 |
Isoelectric point | 4.98 |
Molecular weight | 20831.70 |
Publications | PubMed=21536894
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | chromatin GO:0000785 IBA:GO_Central
mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IBA:GO_Central
|
GO - Biological Process | positive regulation of transcription by RNA polymerase II GO:0045944 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP26572
No repeats found
No repeats found
|