<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26532

Description Nuclear hormone receptor E75
SequenceMSSPYHVVQLAAHRLSPSMPTMDSTVSSAKPEPELNIEFDGTTVLCRVCGDKASGFHYGVHSCEGCKGFFRRSIQQKIQYRPCTKNQQCSILRINRNRCQYCRLKKCIAVGMSRDAVRFGRVPKREKARILAAMQQTPPSRSQEKVVAAELENEQRLLATVVRAHLDTCDFTRDKVAPILARARETPNYTACPPTLACPLNPNPQPLTGQQELLQDFSKRFSPAIRGVVEFAKRIPGFSLLAQDDQVTLLKAGVFEVLLVRLACMFDAQTNSMICLNGQVLKRESIHNSSNARFLMDSMFDFAERVNSLGLSDAELGLFCSVVVIAADRPGLRNTDLVERMHNKLRNALQTVLAQNHPQHPDILRELLKKIPDLRTLNTLHSEKLLAFKMTEQQQQLQAQQQHQQQQQQQQQQQQQQTQQQQQQQQQQTQHVITAQQQQQQQQQQQQQQQQQQQQQQQPHWPMEEEPPASWSSASDVTLDEAVKSPLGSVSSTESTCSGEVASLTEYHHVAPPSSHHASSAPLLAATLAGGLCPHRLRANSGSTSSGDDELHRSAMSKTPQPPQCPRFRKLDSPSDSGIESGTEKPDKPASSSASSAPTSVCSSPRSEDKEVEDMPVLKRVLQAPPLYDTNSLMDEAYKPHKKFRALRQKDSAEAEPAVVVQHTQSQLHLHLTSPPARSPPATQTAQVQCQQTASLLSSTHSTLARSLMEGPRMTPEQLKRTDIIHNFIMHGEASPRSPAASPSPAEQCASTTTVTARSTQGSQGLLQCATTSYSTRWPATSVITTTTGARQQQQQQQHQQQQQQKQQQQQQKQQQQQRQQQQQQRQQQQQQQQQQQQSSSDYLAVGNSPASSPRYLSAAATSSTSTSPRPTSSTAATLVLSGCPSNMMELQVDIADSQQPLNLSKKSPSPSPSPRPLVGPCKALSLEA
Length929
PositionKinase
OrganismHarpegnathos saltator (Jerdon's jumping ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Ponerinae> Ponerini> Harpegnathos.
Aromaticity0.04
Grand average of hydropathy-0.739
Instability index76.73
Isoelectric point8.94
Molecular weight102854.23
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nuclear receptor activity	GO:0004879	IEA:InterPro
sequence-specific DNA binding	GO:0043565	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26532
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     210.65|      19|      19|     404|     422|       1
---------------------------------------------------------------------------
  394-  412 (43.48/14.06)	QQQLQAQQQHQQQQQQQQQ
  413-  429 (39.32/12.08)	QQQQQTQQQQQ..QQQQQT
  430-  448 (39.88/12.34)	QHVITAQQQQQQQQQQQQQ
  801-  819 (42.76/13.71)	QQQQQKQQQQQQKQQQQQR
  820-  838 (45.22/14.88)	QQQQQQRQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     258.72|      73|     344|     491|     567|       2
---------------------------------------------------------------------------
  491-  567 (124.06/73.10)	SSTESTCSGEVAS..LTEYHHVAP.PSSHHA.....SSAPLLA...AT...LAGGL......CPH.RLRA..NSGSTSSGDDELHRSAMsktpQPPQCPR
  591-  657 (54.81/23.22)	SSSASSAPTSVCSspRSEDKEVEDmPVLKRV.....LQAPPLY...DTnslMDEAY......KPHkKFRAlrQKDSAEAEP...................
  662-  737 (79.85/38.98)	QHTQSQLH...LH..LTSPPARSP.PATQTAqvqcqQTASLLSsthST...LARSLmegprmTPE.QLK.......RT...DIIHNFIM....HGEASPR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.34|      12|      15|     858|     869|       3
---------------------------------------------------------------------------
  858-  869 (20.43/10.94)	SAAATSSTSTSP
  874-  885 (21.91/12.28)	STAATLVLSGCP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.54|      18|      18|      89|     106|       5
---------------------------------------------------------------------------
   87-  104 (33.31/24.43)	QQCSILRINRNRCQYCRL
  105-  122 (29.23/20.46)	KKCIAVGMSRDAVRFGRV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.05|      15|      18|     748|     763|       6
---------------------------------------------------------------------------
  748-  763 (22.46/16.94)	QCAsTTTVTARSTQGS
  768-  782 (27.60/16.41)	QCA.TTSYSTRWPATS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.07|      11|      15|     123|     133|       8
---------------------------------------------------------------------------
  123-  133 (17.99/11.58)	PKREKARILAA
  139-  149 (18.08/11.68)	PSRSQEKVVAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.91|      13|      15|     167|     181|      10
---------------------------------------------------------------------------
  167-  181 (19.05/20.99)	DTCDFTrdKVAPILA
  185-  197 (25.86/18.95)	ETPNYT..ACPPTLA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26532 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) QLQAQQQHQQQQQQQQQQQQQQTQQQQQQQQQQTQHVITAQQQQQQQQQQQQQQQQQQQQQQQPHWPMEEEPPASWSSASDVTLDEAVKSPLGSVSSTESTCSGEVASLTEYHHVAPPSSHHASSAPLLAATLAGGLCPHRLRANSGSTSSGDDELHRSAMSKTPQPPQCPRFRKLDSPSDSGIESGTEKPDKPASSSASSAPTSVCSSPRSEDKEVEDMPVLKRVLQAPPLYDTNSLMDEAYKPHKKFRALRQKDSAEAEPAVVVQHTQSQLHLHLTSPPARSPPATQTAQVQCQQTASLL
2) STHSTLARSLMEGPRMTPEQLKRTDIIHNFIMHGEASPRSPAASPSPAEQCASTTTVTA
3) WPATSVITTTTGARQQQQQQQHQQQQQQKQQQQQQKQQQQQRQQQQQQRQQQQQQQQQQQQSSSDYLAVGNSPASSPRYLSAAATSSTSTSPRPTSSTAATLVLSGCPSNMMELQVDIADSQQPLNLSKKSPSPSPSPRPLVGPCKALS
396
699
778
697
757
926










Molecular Recognition Features






MoRF SequenceStartStop




NANANA