<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26530

Description Mediator of RNA polymerase II transcription subunit 14
SequenceMVHFKVETLQCRVGLNPQHLQSLHIKVQPLQEHKDQWSLEELQIIEKFFDTRAATPPYKPNTLSGFGKLLNVPFNVLKDIVQLMKLELVPSLVQQQQLKWSVQWCLRIPPSATPIVPTGMAAMIVCRTKTLFFLQITRIGIQYQGEAPSMVLPLVYDVSSNNTQLAEKRDPSPAFATASMHLKRFSDYASTQPECSLFPTVRDLLANFSLPSEPPILSQVTSSAAGQVTPAQQQIQNTAMQLHSPMASGQGPPQGPYGVQGMLPMGMMNGLPQ
Length273
PositionTail
OrganismHarpegnathos saltator (Jerdon's jumping ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Ponerinae> Ponerini> Harpegnathos.
Aromaticity0.07
Grand average of hydropathy-0.127
Instability index51.07
Isoelectric point8.67
Molecular weight30272.86
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26530
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.46|      10|      18|     245|     254|       2
---------------------------------------------------------------------------
  245-  254 (21.49/11.64)	PMASGQGPPQ
  264-  273 (21.97/12.07)	PMGMMNGLPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.38|      12|      21|     175|     186|       5
---------------------------------------------------------------------------
  175-  186 (21.75/15.54)	FATASMHLKRFS
  198-  209 (21.63/15.41)	FPTVRDLLANFS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26530 with Med14 domain of Kingdom Metazoa
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