<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26521

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVTGPTDQGMQADVIFVIEGTAVNSAYLNDLKASYIIPTLEYFNQGGIEDREYISEQNSTTLYGIVVYHAADCLPAPSTETFGPYTNPHKVLVILDKLEMVGGKGESYANIGEGLATGLQCFEDLQLKREPNTASQKHCILICNSPPYQIMIQECYKFAGHTIEQLATIYQERNINISILSPRKIPALFKLFEKAGGDLQSSQKKNYAKDPRHLVLLRNYNLKERPVSPATGGNVHNTTATAAQIPLSPLQSNDSPNTNQVQQNIAPPSQPQGSPFRNQTPQNITSVHQTVTSSMAAPMNTARPPYNSQIAAPPNYHPTSLSPRTTHTRWMRPFIAPGTTAPTNAQNSSALIAQLTQPPSLGLNVATFGQRLDGGNNVMAPNPQQQQQLTQQQQQQMRLTMQLQQQNAQQATMSMNAQPTHSQPGSQLTVSCMSQSVPTQVPQTVTASQAPVSVSSVTQQIAPPQTQGNVSTVQGPVQGQQLVQRERQNIWQGILEWIEKAKNPTDAQKQTRHVPCQVSANSKDGDPELKADTWPPKLIMQLMPKQLIGNIGSSYLKNSKSVIFHPTPCEALESLTKMMSAGFAGCVHFTSVPPSPACEIKVLILLYTLEKKSYLGFIPNDQTAFVDSLRKVIQQQKTSHASMRHGQANPGPGNTIPAPMPTTGTQGGILMSQTNTMAMGGGQITQNVISNNTVPQTLSSTVPQTQINMQNSGISGPQANAAAGGMITQQRPPFDDLEIARHQNLLKIQHLRQTLEAAQQQEAQYKSQLEVNIQQNLEVAQQQEMQYKQQLEAQQAQRGLNPAAMANQQANTQRLMRPVSASNLGLRHLLQQPQSQYRQQVFGVQQQMVGPRGQLTRPMAPGNTQNQQFEDVPNDFMSF
Length879
PositionUnknown
OrganismHarpegnathos saltator (Jerdon's jumping ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Ponerinae> Ponerini> Harpegnathos.
Aromaticity0.05
Grand average of hydropathy-0.534
Instability index56.50
Isoelectric point8.80
Molecular weight96324.74
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26521
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     159.63|      35|      51|     781|     815|       1
---------------------------------------------------------------------------
  376-  411 (46.80/15.28)	NNVMAPNPQQ............Q...QQ...........ltqqQQ..QQMRLTMQ...LQQQNAQ....QA
  412-  453 (34.99/ 9.53)	T..MSMNAQP.........THSQpgsQL.........tvscmsQS..VPTQVPQT...VTASQAP....VS
  674-  725 (34.10/ 9.10)	TNTMAMGGGQitqnvisnnTVPQ...TL...............SStvPQTQINMQnsgISGPQAN.aaaGG
  800-  853 (43.74/13.79)	LNPAAMANQQ.........ANTQ...RLmrpvsasnlglrhllQQ..PQSQYRQQ...VFGVQQQmvgpRG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.94|      17|      17|     244|     260|       2
---------------------------------------------------------------------------
  226-  240 (19.80/ 6.37)	..PVSPATGGNVHNTTA
  244-  260 (31.68/14.82)	QIPLSPLQSNDSPNTNQ
  264-  279 (29.46/13.24)	NIA.PPSQPQGSPFRNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.38|      23|      37|     735|     761|       4
---------------------------------------------------------------------------
  735-  761 (31.48/32.95)	DDLEIARHQNLlkiQHlRQTLEAAQQQ
  775-  797 (40.90/27.30)	QNLEVAQQQEM...QY.KQQLEAQQAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.76|      20|      37|     288|     309|       6
---------------------------------------------------------------------------
  288-  309 (32.74/23.10)	HQTVTSSMAAPMNTArpPYNSQ
  327-  346 (40.02/21.62)	HTRWMRPFIAPGTTA..PTNAQ
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26521 with Med25 domain of Kingdom Metazoa
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