<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26520

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMNGLTKEQQEAAVRQFLSMAAVMTNHKRLQLLLSLLENLVQTSVLPARLVCECILSCDKLQYQLEDFWVECFTVLRRIIGGVDYKGVREIMKACKEKAQTIPARLDASVQPQLKALENILEHIFDRNSCLLPSYFIVNEIQKAYPDNKNWPHWKLAKLLSSFVEGFRNTAQMVSIVGHSKMLPVVEHTGYADHLINPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCIVLEEQLVELVILAMERSENETLPAEGTDGTVANHWVWLHLSSQLIYFVLFQFACFPSTVMAIHDKLAGRELRKGRDHLMWVLLQFISGSIQRNPLSNFLPVLKLYDLLYPEKEPLPVPDYSQALCTHQMAITCIWIHLLKKAQSEHSNIHRPIPHTLKVHHEFLQHLVMPNTSLCMGSDYRIALLCNAYSTNQEYFSRPMAALVDTILGTQKGQQQQPLQTLQNNAALANGPTTPLSMSILDSLTVHSKMSLIHSIVTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKTLVSAESEELNRALVLTLARSMHVTGTGAETLSGTWCKDLLNTIMQNTPHSWAYHTLECFPPVLSEFFQQNSVAKENKQQIKKAVEEEYRNWASMSNENDIIAHFSVPGTPPLFLCLLWKMILEIDRISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKYNIVTIDRLVLCLALRTQEGSEAQVCFFIIQLLLLKSAEFRNRVQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSGGPSQYQSLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLETLLEHLGCLYKFHDRPVTYLYNTLHYYERKLRDRPPLKRRLVSAVLGSLREIRAPGWALSEAYQMYMTRSADDVVTWIPELDYYIRLVRRIVETMSGTAHFPATDWRFNEFPNPAAHALYVTCVELMAVPVAPNLVANSLLDVVAKGYTVVPSDEIHLWINCVGLLLAALPECYWSALHDRLVETISSPGLANWQYNNLTPFQMFNFNTTHNCLLENKYSYMLALAHSVWHHAGVGQITTMPRFIKEKLQPVVNSEEQLIYACHLIGPTLARFNAERPQCVVELAVCLYEMLEQVDRAQPLLRYMDSVCDLLYHVKYMFVGDMMKNEVECIIRRLKYPLQRRLRFITHLNLEEIHTS
Length1307
PositionTail
OrganismHarpegnathos saltator (Jerdon's jumping ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Ponerinae> Ponerini> Harpegnathos.
Aromaticity0.09
Grand average of hydropathy-0.049
Instability index48.33
Isoelectric point7.20
Molecular weight149956.57
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26520
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     686.63|     217|     260|     760|     993|       1
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  760-  993 (345.50/245.74)	WkmILEIDRISPIAYKILERIGAralSAHLrKFCDYLVFEFANSVGGQHVNKCVDTINDMIWKyNIVTIDRL.VLCLALRTQEGSEAQVCFFIIQLLLLKSAE.....FRNRVQEFVkensPEHwKQSNWHEKHLAFHRKFPEKFAPEGIME.QTSGGPSQYQSLPVYFGNVCLRFLPVFdivVHRYLEipPVIKSLETLLE..HL.G.CLYKFH.DRPVTYLYNTLHYYER.KLRDR.PPLKRRLVS
 1027- 1257 (341.13/199.71)	W..IPELDYYIRLVRRIVETMSG...TAHF.PATDWRFNEFPNPAAHALYVTCVELMAVPVAP.NLVANSLLdVVAKGYTVVPSDEIHLWINCVGLLLAALPEcywsaLHDRLVETI....SSP.GLANWQYNNLTPFQMFNFNTTHNCLLEnKYSYMLALAHSVWHHAGVGQITTMPRF...IKEKLQ..PVVNSEEQLIYacHLiGpTLARFNaERPQCVVELAVCLYEMlEQVDRaQPLLRYMDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     250.74|      75|     298|      96|     171|       2
---------------------------------------------------------------------------
   96-  171 (124.81/87.77)	EKAQTIPARLDASVQPQLKALENILEHIFDRNSCL.LPSYFIVNEIQKAYPDNKNWPHWKLAKLLSSFVeGFRNTAQ
  395-  470 (125.93/84.19)	KKAQSEHSNIHRPIPHTLKVHHEFLQHLVMPNTSLcMGSDYRIALLCNAYSTNQEYFSRPMAALVDTIL.GTQKGQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.55|      19|      30|     527|     545|       3
---------------------------------------------------------------------------
  527-  545 (30.31/21.38)	LAPALVETYSRLLVYTEIE
  556-  574 (33.23/24.30)	LLPTVFKSHAWGTLYTLLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     109.61|      34|     114|     577|     614|       4
---------------------------------------------------------------------------
  577-  614 (55.55/53.86)	SYRMHHIQ..PhyrvQLLSHLHSLAAVPQTNQTQLHLCVE
  692-  727 (54.06/39.73)	SWAYHTLEcfP....PVLSEFFQQNSVAKENKQQIKKAVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.15|      28|     388|     259|     290|       5
---------------------------------------------------------------------------
  259-  290 (43.33/35.37)	EQLVELVILAMERSENET.LPAEGTDGTvanhW
  649-  677 (43.83/25.97)	EELNRALVLTLARSMHVTgTGAETLSGT....W
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26520 with Med23 domain of Kingdom Metazoa
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