<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26513
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MAYSVNISIEAPIENQIQEISYDGQEIYQAPLTLSENLAKIAQKIDFSKTNGDEISKEQLEGGEKSEEDPKDSASFQSSLWPWDSIRNKLRSALTEVCVLADVLAIAKEKNYMVLDPVPQDPVEVKPMMQVYARKKALTGAANLIIHGAQRLQNSQAELTKNRSTPDFHIELLRLRQNWRLKKVANSIIGDLSYRTAGSKYTQTGMFEVTKAEDEERSNNSPPASPNAGGSTSGQPHGPSNSKASALRVTIPSELQGVAYIEVLCQKDQEDLCSANISLLNSSTNSSNADMHWQQKLEAAQNVLFCKELFSQLAREAVHLRAPIPHMVVGNQIMATVLPGIQLIIGLCHSTGNDKKHTAPSPHKTDHDHVLEHSLHQLLREVHHKNTHHPLPHPSSGPLGPSKRRCLAGPTAADRYELLEMAKSQTLLEQIIQQAQHFFMRLRTEYVLDTIAKEVKDPLIVSHWNALNSPTQSCVKINILTHGYDSVCRTSLVVHVGEKSLKCICRDGRVMHMSYEPQELRDLIFCQIYQHQITAVQALAKCMGWQFLANSSHLGVGSVEPLGNASSCILASPIGDRMIAVRCEPQTGVQVSIAHSPRKDFFPGQLVRERKWENLGGSFKEVRWDKMEGKNFLNKMELLMASLTSS |
Length | 646 |
Position | Head |
Organism | Harpegnathos saltator (Jerdon's jumping ant) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea>
Formicidae> Ponerinae> Ponerini> Harpegnathos.
|
Aromaticity | 0.05 |
Grand average of hydropathy | -0.388 |
Instability index | 48.05 |
Isoelectric point | 6.96 |
Molecular weight | 71868.13 |
Publications | PubMed=20798317
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
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Interaction
Repeat regions
Repeats |
>MDP26513
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 167.26| 51| 66| 277| 330| 1
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277- 330 (78.03/64.46) ISLLNSSTNSSNADMHWQQKLEaAQNVLfcKELFSQLAREAVH..LRAPIPHMVVG
345- 397 (89.23/60.59) IGLCHSTGNDKKHTAPSPHKTD.HDHVL..EHSLHQLLREVHHknTHHPLPHPSSG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 194.45| 62| 160| 398| 468| 3
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398- 468 (93.01/96.05) PLGPSKRRCLAGPTAaDRYeLLEMAKSQTLLEQIIQQA..QHFF....MRLRTEYVLDTIAKEVKdplivshWNALN
561- 628 (101.44/76.32) PLGNASSCILASPIG.DRM.IAVRCEPQTGVQVSIAHSprKDFFpgqlVRERKWENLGGSFKEVR.......WDKME
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