<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26504

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMPGLLVALGTSTSLTEVKTGGRKSEALFITFPFVLPTTETSCHWLKSPEFDRPIGTRQQKFLCSDCLILSMETSKVTSKTSSLKALLLRAWRERWTDLQWGINIKTILPRGVSGDVHNLADCILQQALVGPGPNQLVLSYLKHSLSSQLVSYAAVLQRISKYDAFHKPHCILSLLEFLESIQVGITCRGKPEEDLLAAAVLSIVHWLLQCYLHALTKTPQNNSLIPNSNELDKPASILQQMLNSDFMCAMMYLAKYDDKDLYIDVAKKCQEIERFLKTSNQKSAVPIEDSLKKLCNLEIESLSFEKIRMESITHCLQPLFAVQVLLNPSTETAVFVNQLLMVQRLKSYTNERLYCEIIRACLMCLHNVTGTFKESQWGAFTFLKVPLILKELHAATLNSDEKFEYSQDILDAFELLLQFTPLLDIMDSTCSCNYVECLLNELQKVNLVTEKQAKQISARREGVTAALQKLEPSNTPTSSIPKVIIRAKPTLAGILKTLNADYTKIQEALLSMLYHVLTGNSFELMLAVATVEGKLKTFVAKLIKFNESSKQINEPVPDKTAATRAMLFDVSFLMLCSIVQTYGSDVVLEEGGDSFFEQWVYECMPERNKPKSPQKMLQSVDPARVDALLAQINSPDPDFKSSNLKWHVACQSAMGAVKELLCAWESGVLGAGDVKRALDGLRTAACCLPVCAAAWLCAYMSITHQDALLKPMNMVQHFLTPLPGDEMQDNLKERSSLMFQIIRKMQYDVHPPTQSKTKVLSMSHSIISRQPILEQLESVWQNINQRGWINIQATQSLESLLNTGGSLWFVTNIVKEVLKYRYQEELDQAVDLAFAIFHLDIENCTLDLINHIIPQYLHNSLQNDELVEPQSSILAKLCVYCIFSTLEYINSNPYRGNNRKRVRRELDADELDPLSMSNKLLRLNETGESIPMYGSQSPQVQSTSNGQKSEIILKDPLMTALNNLFTIFSFLAGRDGEISQQTHFIFQFLRLTVQCGKDRTRIVLQGMPQTLVPCLLKALPELFTTDILLRLYDIQTIIGRKATARDLCMLRNINLKPAK
Length1059
PositionTail
OrganismCamponotus floridanus (Florida carpenter ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Formicinae> Camponotus.
Aromaticity0.07
Grand average of hydropathy-0.048
Instability index47.71
Isoelectric point6.71
Molecular weight119326.34
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26504
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     192.99|      60|     161|     646|     711|       1
---------------------------------------------------------------------------
  646-  711 (96.75/99.78)	WHVAcqsamGAVKELL.CAWESGVLGAGDVKRALDGLRTAACCLPVCAAAwLCAYMSITHQ.DALLKP
  808-  869 (96.24/77.25)	WFVT.....NIVKEVLkYRYQEELDQAVDLAFAIFHLDIENCTLDLINHI.IPQYLHNSLQnDELVEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.77|      41|     441|     432|     474|       7
---------------------------------------------------------------------------
  432-  474 (63.53/44.50)	CNYveCLLNELQKVNLVTEKQAKQISARREGVTAALQKLEPSN
  878-  918 (73.25/45.79)	CVY..CIFSTLEYINSNPYRGNNRKRVRRELDADELDPLSMSN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     211.25|      64|     575|     126|     189|      11
---------------------------------------------------------------------------
  126-  189 (111.56/69.90)	QALVGPGPNQLVLSYLKH..SLSSQLV...SYAAVLQRISKYDAFHKPHCILS...LLEFLESIQVGITCRG
  716-  787 (99.69/61.71)	QHFLTPLPGDEMQDNLKErsSLMFQIIrkmQYDVHPPTQSKTKVLSMSHSIISrqpILEQLESVWQNINQRG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.07|      16|      16|     980|     995|      13
---------------------------------------------------------------------------
  980-  995 (29.66/16.91)	QQTHFIFQFLRLT.VQC
  998- 1014 (23.42/11.95)	DRTRIVLQGMPQTlVPC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26504 with Med24 domain of Kingdom Metazoa
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