<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26500
Description |
Mediator of RNA polymerase II transcription subunit 17 |
Sequence | MAYSVNISVEAPIENQIQEISYDGQEIYQAPLTLSENLAKIAQKIDFNKTNGEEIKKEQIEGEKGDEDMKDSTSFQSSLWPWDSVRNKLRNALTEVCVLADVLAIAKEKNYMVLDPVPQEPVEVKPMIQVYARKKALAGAATVLMLGAERLRNCQAELARTKSTPDFHIELLRLRQNWRLKKVSNSIIGDLSYRTAGSKYTQMGMFEVTKAEEEEKNSNSPPASPNAGNNMSGQSHISSNSKMSALRVTIPSELQGVAYIEVLCQKDQEDLCNANISLLNSNTNNSNADMHWQQKLEAAQNVLFCKELFSQLAREAVHLRAPIPHMVVGNQIMATVLPGIQLIIGLCHSTGSDKKPVAPPPHKTDHDHVLEHSLHQLLREVHYKNSQHPFPHPASGPLGPSKRRYLAGPTAADKYELLEMTKSQTLLEQIIQQAQHFFMRLRTEYVLDTIAKEVKDPLIVSHWNALNSPTQSCVKINILTHGYDSVCRTTMIVHVGEKSLKCVCRDGRVMHMSYEPQELRDLIFCQIYQHQINAVQALAKCMGWQFLANSSHLGLGSVEPLGNASSCILASPIGDRMIAVRCEPQMGVQVAIAHSPRKDFFPGQLVRERKWENLGGSFKEVRWDKMEGKNFLNKMELLMSSLMSS |
Length | 645 |
Position | Head |
Organism | Camponotus floridanus (Florida carpenter ant) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea>
Formicidae> Formicinae> Camponotus.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.365 |
Instability index | 50.45 |
Isoelectric point | 7.07 |
Molecular weight | 72314.17 |
Publications | PubMed=20798317
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364140
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26500
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 61.86| 18| 66| 311| 329| 1
---------------------------------------------------------------------------
311- 329 (30.58/22.16) QLAREaVHLRA...PIPHMVVG
376- 396 (31.27/18.22) QLLRE.VHYKNsqhPFPHPASG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 81.38| 25| 39| 189| 213| 2
---------------------------------------------------------------------------
189- 213 (43.18/34.75) G.DLSYRTAGSKYTQMGMFEVTKAEE
228- 253 (38.20/29.80) GnNMSGQSHISSNSKMSALRVTIPSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 57.77| 17| 26| 11| 27| 6
---------------------------------------------------------------------------
11- 27 (29.59/18.20) APIENQIQEISYDGQEI
39- 55 (28.19/17.04) AKIAQKIDFNKTNGEEI
---------------------------------------------------------------------------
|