<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26498

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSSETQIASIVNDILKVEAIEEAFSCVLVHQPNNESEKITTWQNELKGVMTGLTKEQQEAAVRQFLSMAAAMTNHRRLQLLLSLLQNLVQSNVLPARLVCECILSCDKLQYQLEDFWVECFVLIRHIIGGVDYKGVREIMKGCKEKAQTIPARLNASVQPQLKALENVIEYIFDRNACLLPGYFIVNEIQKAYPDNKNWPHWKLAKLLSNFVESFRNTAQMVSIIGHSKMLPVVEHTGYADHLINPWLLDPTTLKFSLKGNLPYDPDLLKPQTELLRYVLEQPYSRDMVCSMLGLQKQHKQRCIVLEEQLVELVILAMERAENESLPAEGTDGTVANHWVWLHLSSQLIYFILFQFACFPSIVMAIHDKLAGRDLRKGRDHLMWVLLQFISGSIQRNPLSNFLPVLKLYDLLYPEKEPLPVPDYTQALCTHQMAITCIWIHLLKKAQSEPVSNIHRPIPHTLKVHHEFLQHLVMPNTSLCMGSDYRIALLCNAYSTNQEYFSRPMAALVDTILGTQKNQQQQPLQILQNTAALANGPTTPLSMSILDSLTVHSKMSLIHSIVTHVIKLAQSKSNMALAPALVETYSRLLVYTEIESLGIKGFISQLLPTVFKSHAWGTLYTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVPQTNQTQLHLCVESTALRLITGLGSAEVQPQLSRFLSEPKTLVSAESEELNRALVLTLARSMHVTGTGADSLSGTWCKELLNTIMQNTPHSWANHTLQCFPPVLSEFFQQNSIPKENKQQINKAVEEEYRNWSSMSNENDIIAHFSVPGTPPLFLCVLWKMILKTDCISPIAYKILERIGARALSAHLRKFCDYLVFEFANSVAGQHVNKCVDSINDMIWKYNIVTIDRLILCLALRTQEGNEAQVCFFIIQLLLLKAAEFRNRLQEFVKENSPEHWKQSNWHEKHLAFHRKFPEKFAPEGIMEQTSGGPSQYQSLPVYFGNVCLRFLPVFDIVVHRYLEIPPVIKSLEILLEHLGCLYKFHDRPVTYLYNTLHYYERKLRDRPLLKRRLVSAVLGSLREIRAPGWALSEAYQKYMTRLNDDAVQWIPELDYYIRLVQRIVETMSGTAHFPATDWRFNEFPNPAAHALYVTCVELMALPVAANLVANSLLDVVAKGYTVVPSDEIHLWINCIGLLLAALPECYWSALHDRLVETISSPALANWQYKNLTPFQIFNFNITHNSLLENKYSYMLALAHSVWHHAGVGQITTMPQFIKEKLQPVVSSEEQLIYACHLIGPTLVRFNAERPHCVVELTVSLYEMLERVDHTQAHLNYMDTICDLLYHIKYMFVGDMMKNEVECIIRRLRPALQMRLRFISHINIEKIHTS
Length1357
PositionTail
OrganismCamponotus floridanus (Florida carpenter ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Formicinae> Camponotus.
Aromaticity0.09
Grand average of hydropathy-0.028
Instability index48.13
Isoelectric point6.96
Molecular weight155476.91
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26498
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     648.85|     204|     259|     808|    1028|       1
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  808- 1028 (324.38/220.56)	VLWkmILKTDCISPIAYKILERIGAralSAHLrKFCDYLVFEFANSVAGQHVNKCVDsINDMIWKYNIVTIDRL.ILCLALRTQEGNEAQVCFFIIQLLLLKAAE.....FRNRLQEFVkensPEHwKQSNWHEKHLAFHRKFPEKFAPEGIME.QTSGGPSQYQSLPVYFGNVCLRFLPVFdivVHRYLEipPVIKSLEILLE..HL.G.CLYKFH.DRPVTYLYNTLHYYE
 1075- 1290 (324.47/179.71)	VQW..IPELDYYIRLVQRIVETMSG...TAHF.PATDWRFNEFPNPAAHALYVTCVE.LMALPVAANLVANSLLdVVAKGYTVVPSDEIHLWINCIGLLLAALPEcywsaLHDRLVETI....SSP.ALANWQYKNLTPFQIFNFNITHNSLLEnKYSYMLALAHSVWHHAGVGQITTMPQF...IKEKLQ..PVVSSEEQLIYacHLiGpTLVRFNaERPHCVVELTVSLYE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     404.08|     128|     298|     145|     289|       2
---------------------------------------------------------------------------
  145-  278 (212.26/160.59)	EKAQTIP.ARLNASVQPQLKALENVIEYIFDRNACLLPG..YFIvNEIQKAYPDNKNWPHWKLAKLLSNFVESFRNTAQM.VSIIGHSKMLPvvehTGYADHLiNPWLLDPTTL..KFSL..............KGNLPYDPDLLKPQTELLRY
  444-  591 (191.83/111.95)	KKAQSEPvSNIHRPIPHTLKVHHEFLQHLVMPNTSLCMGsdYRI.ALLCNAYSTNQEYFSRPMAALVDTILGTQKNQQQQpLQILQNTAALA....NGPTTPL.SMSILDSLTVhsKMSLihsivthviklaqsKSNMALAPALVETYSRLLVY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     112.36|      29|     579|      67|     101|       4
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   67-   95 (48.38/27.04)	SMAA.AMTNHRRL......QL.....LLSLLQNLVQSNVLP
  647-  681 (35.34/16.02)	SLAAvPQTNQTQL......HLcvestALRLITGLGSAEVQP
  712-  742 (28.64/13.33)	SMHV.TGTGADSLsgtwckEL.....LNTIMQNTPHS....
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26498 with Med23 domain of Kingdom Metazoa
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