<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26486

Description Mediator of RNA polymerase II transcription subunit 25
SequenceMVTGPTEHGIQADVIFVIEGTAVNGAYLNDLKTNYLIPTLEYFSQGGIEDREYVSENSTTLYGIVVYHAADCLPSPCTETFGPYSNPHKLLVVLDKLEMVGGKGESCANIGEGLATGLQCFEDLQLRREPNTASQKHCILICNSPPYQIMIQESYKFAGHTIEQLAAIYQERNINISILSPRKIPALYKLFEKAGGDLQSSQTKNYAKDPRHLVLLRNYNLKERPVSPQMGGNVHNTSSVTQIPLSPLQSNDSPNTNQVQQNIAPPNQQQSPAFRNQTPQNITVHQNVPSSMAAPMNTARPPYNPQIAAPPNYHPAGVNIATRARWMRPYITPGAAAPTNTQGSALIAQLTQPPSSLGLNVAAFGQRLDVKRVVQEAKRLSCETSQAA
Length388
PositionUnknown
OrganismCamponotus floridanus (Florida carpenter ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Formicinae> Camponotus.
Aromaticity0.06
Grand average of hydropathy-0.391
Instability index62.65
Isoelectric point7.62
Molecular weight42401.48
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26486
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     160.25|      40|      42|     280|     321|       1
---------------------------------------------------------------------------
  259-  279 (23.85/ 6.77)	....VQQNI....APPNQQQSPAFRNQTP.............
  280-  321 (67.49/39.53)	QNITVHQNVPSSMAAPMNTARPPYNPQIAAPPNyhPAGVNIA
  323-  362 (68.91/34.43)	RARWMRPYITPGAAAPTNTQGSALIAQLTQPPS..SLGLNVA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     170.65|      51|      56|      25|      78|       2
---------------------------------------------------------------------------
   25-   78 (81.38/75.82)	GAYLNDLKTNYLIPTLEYFSQGGiEDREYVSENSTTlyGIVVYHAADCLPSPCT
   82-  132 (89.27/69.68)	GPYSNPHKLLVVLDKLEMVGGKG.ESCANIGEGLAT..GLQCFEDLQLRREPNT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.04|      10|      33|     188|     197|       3
---------------------------------------------------------------------------
  188-  197 (18.96/11.02)	YKLFEKA.....GGD
  219-  233 (14.08/ 6.59)	YNLKERPvspqmGGN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26486 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RPVSPQMGGNVHNTSSVTQIPLSPLQSNDSPNTNQVQQNIAPPNQQQSPAFRNQTPQNITVHQNVPSSMAAPMNTARPPYNPQIAAPPNYHPAGVNIATRAR
224
325










Molecular Recognition Features






MoRF SequenceStartStop




1) RARWMRPYI
323
331