<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26482

Description Mediator of RNA polymerase II transcription subunit 26
SequenceMQRYCSELTEKLLKSLDKEYNVVDMRTVVDVITALEKTTITKEVLEITRLGKHINELRRKTSNETLAKRAKDLVRHWRDMVLPSVHSTPQPTLADTAPPALNGAKEVALRNFKPQSPALRGLLKPHSPLLKDATPLRVLSPALSMHSDHSRSPNASTNSKQSITPTSNHRISSCSRNASPVLSSSSQNHTIEAVPRTHSSNKRLRKEESGKEQHQCYQSPHGIEPMVEQVPAKNQRLNGENISGNLNSQVPSPTLKERISSSFTETDSLEVTDDNPGPKKRGRKKGSKSAKRQPFLEDSVKKKLASISRTPKLKTTQEIVAQLQAGRSNCSPGNTNALPSQSVVEPPNTEDVLRSSSNDQVSKYCSSQNLHRSLASSETSSTGKTQTTRFAENWPEACQDRLREDDKSTGIDQSSTCRSPSHRDLTVEEILAKLPPLDPSSIDWGEDEEQNYIECSPPPRNATAEDLERLHTQSIEGLNGNFQLSSMTACRSDGDEHSNARDEENKVSSGLSNVDSVKSVHNNQTDSAEFREWHQMLARSSYQGEILNIMPYVIID
Length556
PositionUnknown
OrganismCamponotus floridanus (Florida carpenter ant)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Hymenoptera> Apocrita> Aculeata> Formicoidea> Formicidae> Formicinae> Camponotus.
Aromaticity0.03
Grand average of hydropathy-0.871
Instability index65.86
Isoelectric point8.01
Molecular weight61699.93
Publications
PubMed=20798317

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26482
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     289.88|      73|      86|     141|     213|       1
---------------------------------------------------------------------------
  141-  186 (66.47/28.88)	............................................PALSMHS..............................DHSRSPNASTN.SKQSITPTS.NHRISSCSRNASPVLSSSS
  187-  264 (79.67/36.00)	QNHTIEAVPRTHSSNKRLRKEESGKEQhqcyqsphgiepmveqvPA...KN..............................QRLNGENISGNlNSQVPSPTL.KERIS..........SSFT
  265-  342 (97.45/45.60)	ETDSLEVTDDNPGPKKRGRKKGSKSAK.........rqpfledsVKKKLAS...............................ISRTPKLKT...TQEIVAQL.QAGRSNCSPGNTNALPSQS
  345-  423 (46.28/17.98)	EPPNTEDVLRS.SSNDQVSKYCSSQN.........................lhrslassetsstgktqttrfaenwpeacqDRLREDDKSTG.IDQSSTCRSpSHR................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.59|      22|     356|      95|     122|       2
---------------------------------------------------------------------------
   98-  122 (30.47/31.39)	PPALNGAKEvALRNFKPQSpaLRGL
  457-  478 (40.13/19.64)	PPPRNATAE.DLERLHTQS..IEGL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26482 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLKDATPLRVLSPALSMHSDHSRSPNASTNSKQSITPTSNHRISSCSRNASPVLSSSSQNHTIEAVPRTHSSNKRLRKEESGKEQHQCYQSPHGIEPMVEQVPAKNQRLNGENISGNLNSQVPSPTLKERISSSFTETDSLEVTDDNPGPKKRGRKKGSKSAKRQPFLEDSVKKKLASISRTPKLKTTQEIVAQLQAGRSNCSPGNTNALPSQSVVEPPNTEDVLRSSSNDQVSKYCSSQNLHRSLASSETSSTGKTQTTRFAENWPEACQDRLREDDKSTGIDQSSTCRSPSHRDLTVEEILAKLPPLDPSSIDWGEDEEQNYIECSPPPRNATAEDLERLHTQSIEGL
2) NFQLSSMTACRSDGDEHSNARDEENKVSSGLSNVDSVKSVHNNQTDSAEFREWH
3) SVHSTPQPTLADTAPPALNGAKEVALRNFKPQSPALRGLLKPHS
129
481
84
478
534
127










Molecular Recognition Features






MoRF SequenceStartStop




1) KRQPFLEDSVKKKL
291
304