<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26455
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MDLLYTVSRKLNNNTINPLKQFESLTSGCSLCSISNQNLLAFTTVTTVTDTTANSWGSHVYVADLNSPWLAHKVTSNLCTITVLEWDLGGENLVIADLNGKVQIWGMKEHILNEWVCYGSAVFHGEKILSAAFFHNGRKTSLVIEKKDNFQYSEKFSHHRVAPSVKSFGGRPLEGCLVVSATGMVGIIVLTKDLQNSTLHSVSESLGTMRNRITSADICYGKNGQFLIAVSSGNVKLPIQCYRVSVKKVDDKCIITSQALPSFFLQNIPVNESSCRKIVELKFVVREDTDSLVVAANGESGSIIEIWELREKPLPIHKLFQSKHSAPVEPLKTVASFC |
Length | 338 |
Position | Tail |
Organism | Pediculus humanus subsp. corporis (Body louse) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Paraneoptera> Psocodea> Phthiraptera> Anoplura> Pediculidae>
Pediculus.
|
Aromaticity | 0.08 |
Grand average of hydropathy | 0.005 |
Instability index | 24.87 |
Isoelectric point | 8.27 |
Molecular weight | 37280.42 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP26455
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 39.78| 11| 47| 56| 69| 1
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56- 69 (15.33/20.04) WGSHVYVadLNsPW
105- 115 (24.44/15.12) WGMKEHI..LN.EW
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 65.70| 21| 44| 147| 171| 3
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147- 171 (29.39/34.68) KDnFQYSekfSHHRVAPSVKSFGGR
192- 212 (36.31/25.57) KD.LQNS...TLHSVSESLGTMRNR
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