<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26403

Description Uncharacterized protein CDKE-2
SequenceMADGIAKRARPAWLQQYELLGKIGEGTYGLVYLAKSKLVSNRGVKIAIKKFKQSKEGDGVSPTAIREIMLLRECMHENVVKLVDVHINHADMSLYLAFEYAEHDLYEIIRHHREKLLFQINPYTVKSLLWQILNGINYLHSNWIIHRDLKPSNILVMSGDGDEQGLVKIGDFGLARIYQAPLKPLSDNGVVVTIWYRAPELLLGAKHYTCAVDMWAVGCIFAELLTLKPLFQGAEDKTGPNPFQLDQLDKIFKVLGHPTTERWPMLSNLPHWLANRQLIQSRKYDNPGLHTVVNLQPKGLAFDLLSRMLEYDPVKRITAAQALDHEYFRSDPLPGRNALVYGQPGEKVVQYPARPVDSSTDFEGSGSIQNTQMVRDRKRKQAFFSPLQCGGGSSFLMVSTFRGSQMSTSNSLPASAASAAAASATANAVRPMHHQQMPLVGMQRLQTASMGAFNVGAQPAMAGLAANMFVQRGQQLQQVAHHQQQQQQQQQHQHHQHQQHQVQKLRSFFRS
Length511
PositionKinase
OrganismSelaginella moellendorffii (Spikemoss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Lycopodiopsida> Selaginellales> Selaginellaceae> Selaginella.
Aromaticity0.08
Grand average of hydropathy-0.334
Instability index42.57
Isoelectric point9.42
Molecular weight57437.27
Publications
PubMed=21551031

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26403
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.86|      27|     143|      20|      48|       1
---------------------------------------------------------------------------
   20-   48 (41.99/29.05)	LGKIGEgtYGL..VYLAKSKLVSNRGVKIAI
  166-  194 (43.86/24.33)	LVKIGD..FGLarIYQAPLKPLSDNGVVVTI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.18|      24|      45|     413|     436|       2
---------------------------------------------------------------------------
  413-  436 (41.17/29.17)	PASAASAAAA.SATANAVRPM.HHQQ
  459-  484 (35.01/23.62)	PAMAGLAANMfVQRGQQLQQVaHHQQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26403 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GQQLQQVAHHQQQQQQQQQHQHHQHQQHQVQKLRSFF
2) STSNSLPASAASAAAASATANAVRPMHHQQMPLVGMQ
473
407
509
443










Molecular Recognition Features






MoRF SequenceStartStop




1) LRSFFRS
505
511