<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26390

Description Uncharacterized protein
SequenceMERSVILLFALLIAGAAVVAKEEAAKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTETERLIGEAAKNQAAVNPERTIFDVKRLIGRKFEDKEVQKDMKLFPFKIVNKDGKPYIQVKVKDGETKVFSPEEISAMILTRMKETAESYLGKKIKDAVVTVPAYFNDAQRQATKDAGAIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSILTIDNGVFEVLSTNGDTHLGGEDFDQRVMDYFIKLIKKKHNKDISKDNRALGKLRREVERAKRALSNQHQVRVEIESLFDGVDFSEPLTRARFEELNADLFKKTMGPVKKAMDDANLQKSEIHEIVLVGGSTRIPKVQQLLKDFFDGKEPNKGVNPDEAVAFGAAVQGGILSGEGGDDVKGILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQSAVSIHVYEGERSMTKDNRELGKFDLAGIPPAPRGVPQIEVTFEIDANGILNVRAEDKGTGKSEKITITNDKGRLTQEEIDRMVREADEMAEEDKKQKERVDSRNGLETYLYNMRNTINDKDKLADKIEKEDKEKIEETLKEALEWLDDNNTAEKEDFDDKLKEVEAVCNPIITQIYQKTGGAAGSPSSEDDDSDDDHSEL
Length660
PositionUnknown
OrganismSelaginella moellendorffii (Spikemoss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Lycopodiopsida> Selaginellales> Selaginellaceae> Selaginella.
Aromaticity0.06
Grand average of hydropathy-0.482
Instability index30.63
Isoelectric point5.09
Molecular weight72956.74
Publications
PubMed=21551031

Function

Annotated function
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central
GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central
GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP26390
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.05|      15|      21|      61|      81|       1
---------------------------------------------------------------------------
   61-   76 (23.40/21.96)	ITPSWVAFtETERLIG
   85-   99 (26.64/ 9.25)	VNPERTIF.DVKRLIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     377.66|     127|     193|     180|     315|       2
---------------------------------------------------------------------------
  180-  315 (186.10/127.80)	RQATKDagAIAGLNVARIINEPTA....AAIAYG.LDKKGGE..KNILVFDLggGTFDVSILTIDNGVFEVLSTNGDTHLGGED....FDQRVMDYFIKLIkkKHNKDISKDNRALGKLR.REVERAKRALSnQHQVRVEIESlfDGV
  371-  509 (191.56/106.84)	QQLLKD..FFDGKEPNKGVNPDEAvafgAAVQGGiLSGEGGDdvKGILLLDV..APLTLGIETVGGVMTKLIPRNTVIPTKKSQvfttYQDQQSAVSIHVY..EGERSMTKDNRELGKFDlAGIPPAPRGVP.QIEVTFEIDA..NGI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.67|      25|      32|     545|     575|       3
---------------------------------------------------------------------------
  545-  570 (37.17/36.77)	EADEMAEE.DKKQKERVD..SRNGLEtYL
  579-  606 (31.50/13.25)	DKDKLADKiEKEDKEKIEetLKEALE.WL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP26390 with Med37 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) KGTGKSEKITITNDKGRLTQEEIDRMVREADEMAEEDKKQKERVDSRNGLETYLY
517
571

Molecular Recognition Features

MoRF SequenceStartStop
1) DDHSEL
2) DKLKEVEAVCNPIITQIYQKTGGAA
3) YLYNMR
655
619
569
660
643
574