<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26320
Description |
Mediator of RNA polymerase II transcription subunit 11 (Fragment) |
Sequence | MEPTNAEAGPSTQPHHPPEDDASAVDPVWTTSRTARQIYYLCNVEKKITVLLQRASNAMLCLSLPQTDGPDDKLIVQPDAPNADEPAEDGLPRDVLRKDEMRNEQLAAEIQSYFDVLLEISHEIRSSLAHIRHARMTPSSIIAPDAISPPKGPGQPPQPFTPPAFGVGLPYDEDDAKRRNERGLQEARIERDAWKGILDALMKLKKARDEEGAGEGEDAAMANGGEKAESPGKEDAMQV |
Length | 239 |
Position | Head |
Organism | Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes>
Agaricomycetidae> Agaricales> Schizophyllaceae> Schizophyllum.
|
Aromaticity | 0.04 |
Grand average of hydropathy | -0.731 |
Instability index | 55.95 |
Isoelectric point | 4.73 |
Molecular weight | 26146.90 |
Publications | PubMed=20622885
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26320
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 305.69| 74| 75| 81| 155| 1
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17- 77 (89.11/42.76) P....PEDD.ASAVDPVWTT.SRTARQI......YY..LCNVEKKITVLLQRASNAMLCLS...LPQTDGPdDKL.....IVQ
81- 155 (119.94/63.23) PNAdEPAED.GLPRDVLRKD.EMRNEQLAAEIQSYFDVLLEISHEIRSSLAHIRHARMTPSSIIAPDAISP.PKG.....PGQ
159- 233 (96.64/46.90) PFT.PPAFGvGLPYD..EDDaKRRNERGLQEARIERDAW....KGILDALMKLKKARDEEGAGEGEDAAMA.NGGekaesPGK
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