<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26205
Description |
Uncharacterized protein |
Sequence | MSATLHMIIMALTATPGSCAMEVDKDAVSAMQESVDQLALSMFDSLRLIPFSEEVKGGARGVAPLQQQQPGQPDAAPLRRAVTTNAAWADTVQSLADGVLKQARALDGLIDVLPGAELREDQQMEEIARLDREGKLKRTELAKMVEKAEALSKGVNGSLDQLADHMLGAPR |
Length | 171 |
Position | Middle |
Organism | Ectocarpus siliculosus (Brown alga) (Conferva siliculosa) |
Kingdom | Phaeophyceae |
Lineage | Eukaryota> Sar> Stramenopiles> Ochrophyta> PX clade> Phaeophyceae>
Ectocarpales> Ectocarpaceae> Ectocarpus.
|
Aromaticity | 0.02 |
Grand average of hydropathy | -0.186 |
Instability index | 42.25 |
Isoelectric point | 4.86 |
Molecular weight | 18304.78 |
Publications | PubMed=20520714
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP26205
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 208.66| 54| 55| 58| 111| 1
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16- 53 (50.36/25.03) ............PGSCA.MEVDKDAV...SAMQESVDQLALSMFDSLR.LIPFSE
58- 111 (88.93/48.71) GARGVAPLQQQQPGQPD.AAPLRRAVTTNAAWADTVQSLADGVLKQARALDGLID
115- 164 (69.38/36.71) GAELREDQQMEEIARLDrEGKLKR..TELAKMVEKAEALSKGV...NGSLDQLAD
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|