<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26198

Description Mediator of RNA polymerase II transcription subunit 30-like Protein
SequenceMSAPQHHFMQGLNNSQQTALRNQFASTMQSQMGTTMQNQLPVHMGNQMNNPMMSQMASTLNNPTMPNSQIMGQLNQQYAMNPANQIAQHQGGNMQMQQGSMEFSNNLQHHAMQANQAQMVQQGGAVAPAPQIQAQQQQQQQSKEFNTASLCRIGQETVQDIVSRTQEVFQTLKTIQPPNGTPQSSNASNEKKAKVQEQLRTIRVLFKRLRLIYEKCNENCQLQGMEYTHIESLIPFKDEHDPKHDEKKNSEAYRLACEECKEVMEQVILKNKQLKDVIDHLRRIIWEINTMLTMRRS
Length297
PositionHead
OrganismTribolium castaneum (Red flour beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Tenebrionidae> Tenebrionidae incertae sedis> Tribolium.
Aromaticity0.04
Grand average of hydropathy-0.844
Instability index54.36
Isoelectric point8.57
Molecular weight34009.26
Publications
PubMed=18362917
PubMed=19820115

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of transcription, DNA-templated	GO:0045893	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26198
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     141.50|      26|      29|      67|      92|       1
---------------------------------------------------------------------------
   29-   46 (31.17/10.35)	QSQ.MGTTM.......Q.......NQLPV..HMGN
   49-   66 (26.45/ 7.71)	NNPMMSQMA.......S..TLNNPTM........P
   67-   92 (51.80/21.89)	NSQIMGQLN.......QQYAMNPANQIAQ..HQGG
   93-  124 (32.08/10.86)	NMQ.MQQGSmefsnnlQHHAMQ.ANQ.AQmvQQGG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26198 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSAPQHHFMQGLNNSQQTALRNQFASTMQSQMGTTMQNQLPVHMGNQMNNPMMSQMASTLNNPTMPNSQIMGQLNQQYAMNPANQIAQHQGGNMQMQQGSMEFSNNLQHHAMQANQAQMVQQGGAVAPAPQIQAQQQQQQQSKEFNTAS
1
149










Molecular Recognition Features






MoRF SequenceStartStop




NANANA