<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26185

Description Mediator of RNA polymerase II transcription subunit 24-like Protein
SequenceMVMETKTTSKTSCLKALLLKAWRERWTDLQWGINIKTVLPRGVSGDVYNLADCILQQAVVGAGANQLVLSYLRHSLSAQLVSHAAVLQRLSKYNQLSKVHCVFSLLEFLEGMLPGVTCCGKPEETVLATAILSIACWLLTILLQCKGTAHLTQKASFLLTTLMNDDFYVSMMCLARYSDPELFTETNRKCIELRASLSDSDELSKCVKKLENIDVNILSLPINSEKWPGALIQCWLEVKLVGNPGASTNSLAEQLRLFQKLKGFDGPRLYAELMRGSLLALYDVNQTAHESQWGAFAFLKVPHILLELAGKSDSNSIVSAVELMLQHSPLLDAMDANSSCSSLECLLGELVKARLITEVQLKHLLEKRKPPPSVKLDTAPAAAGIPKVIICAEPTLAGILKTLSTDYHKIQDPLLGMLHQVLTGKSFELILAVATVQGQLRTLVTRLIRFNECSKSGGDKARAQLFDISFLMLVAIVQNYGANAVLDPDGESLFEQWVKSCMVERQRPKAPEQLLRLGDPDTIEMLLQQFNAGESDFKPNIKWQDVLFNMPGVMHEVLVAWEQGALVPSDVKRILDAVRGRMCSLPLAAAAWLCAYMRTAPQENLLKPVNMVQQLLAPPAAEEDSLRERWQLTCEIIRKMQRDVQLPLQTKSSHHLISRQPAVEQLHSAWSGAIRRGWLDHSSAKTLHCLLDTAGPRWLVSAVIQEMLKLRYRDQLQRGVDLALAAFHVDIRACTLELLSHVLPQMLYNDLQADSLMEPHLIALAYLTSYCVYTAFDAFSEEPEEPMAKVARLNEGEDGTLIEQLISTLRQLMTIFEDGIQEGYITQQTYFAFYLIKSLVEVKVSTASALLAAIPPALVTDLLRTLPELFTYPILLHLHDVFNTHGRNNMAKDLCILRNYHLRNVSQESN
Length910
PositionTail
OrganismTribolium castaneum (Red flour beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Tenebrionidae> Tenebrionidae incertae sedis> Tribolium.
Aromaticity0.07
Grand average of hydropathy0.063
Instability index43.12
Isoelectric point6.25
Molecular weight101564.10
Publications
PubMed=18362917
PubMed=19820115

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26185
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     151.98|      49|      86|     329|     381|       1
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  329-  381 (78.44/53.68)	PLLDAMDANSSCSSLECLLG.ELVKARLITEV.QLKHLLEKRKPPPsvklDTAPA
  413-  463 (73.54/42.44)	PLLGMLHQVLTGKSFELILAvATVQGQLRTLVtRLIRFNECSKSGG....DKARA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     275.39|      83|      87|      63|     145|       3
---------------------------------------------------------------------------
    9-   59 (43.82/23.53)	.....................................SKTS..CLKALLlkawrERWTDLQWGINI.....K...TVLPRGVSG.......DVYNLADCILQqaV
   63-  145 (139.39/91.39)	GANQLV..LSYLRHSL.SAQLVSHAAVLQRLSKYNQLSKVH..CVFSLL.....EFLEGMLPGVTCCGKPEE...TVLATAILS.......IACWLLTILLQ..C
  147-  236 (92.19/57.88)	GTAHLTqkASFLLTTLmNDDFYVSMMCLARYSDPELFTETNrkCI.ELR.....ASLSDSDELSKCVKKLENidvNILSLPINSekwpgalIQCWL.........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     259.71|      86|     103|     560|     657|       4
---------------------------------------------------------------------------
  560-  657 (123.01/111.08)	AWEqGAlvpsdVKR.ILDAVRGRM..CSLPLAAAAWLcayMRTAPQEnLLKpVNMVQQL.....LAPPAAEEDSLRERWQLTCEIIRKMQRDvQLPLQTKSSHHLI
  669-  762 (136.70/84.40)	AWS.GA.....IRRgWLDHSSAKTlhCLLDTAGPRWL...VSAVIQE.MLK.LRYRDQLqrgvdLALAAFHVDIRACTLELLSHVLPQMLYN.DLQADSLMEPHLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.81|      21|     460|     383|     403|      10
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  383-  403 (36.74/25.55)	AGIPKVIICAEPTL.AGIL.KTL
  819-  839 (25.10/15.02)	.GIQEGYITQQTYF.AFYLiKSL
  852-  866 (18.97/ 9.48)	AAIP.......PALvTDLL.RTL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26185 with Med24 domain of Kingdom Metazoa
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