<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26184

Description F-box-like/WD repeat-containing protein ebi
SequenceMSFSSDEVNFLVYRYLQESGFQHSAYTFGIESHISRSNINGALVPPAALLSILQKGLQYTEAEISIGEDGLEQRLVESLSLIDAVMPDVVASRQNQQNAQKQPIKSEITDTNGEEAVVSTQNENMEVDTSIEIPTSKATVLRGHESEVFICAWNPTTDLLASGSGDSTARIWDMSDNTASPNQLVLRHCIQKGGTEVPSNKDVTSLDWNCDGSLLATGSYDGYARIWTTDGRLASTLGQHKGPIFALKWNKRGNYILSAGVDKTTIIWDAASGQCTQQFSFHSAPALDVDWQTNTSFASCSTDQCIHVCKLSLDKPIKSFQGHTNEVNAIKWDPQGNFLASCSDDMTLKIWSMKQDNCVHDLQAHSKEIYTIKWSPTGPGTQNPNMNLILASASFDSTVRLWDVERGACIHTLTKHTEPVYSVAFSPDGKFLASGSFDKCVHIWSTQSGQLVHSYKGTGGIFEVCWNSRGDKVGASASDGSVFVLDLRKL
Length490
PositionTail
OrganismTribolium castaneum (Red flour beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Tenebrionidae> Tenebrionidae incertae sedis> Tribolium.
Aromaticity0.08
Grand average of hydropathy-0.308
Instability index37.31
Isoelectric point5.23
Molecular weight53654.27
Publications
PubMed=18362917
PubMed=19820115

Function

Annotated function 
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central

GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central

GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26184
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     337.97|      33|      39|     208|     240|       1
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  153-  183 (48.24/22.40)	WNPTTD.........LLASGSGDSTARI..W.D.MS.DNTASP.NQ.
  208-  240 (58.45/28.41)	WNCDGS.........LLATGSYDGYARI..W.T.TD.GRLASTLGQH
  249-  282 (43.53/19.63)	WNKRGN.........YILSAGVDKTTII..WdA.AS.GQCTQQFSFH
  291-  323 (40.81/18.03)	WQTNTS.........F.ASCSTDQCIHVckL.S.LD.KPIKSFQG.H
  332-  365 (53.71/25.62)	WDPQGN.........FLASCSDDMTLKI..W.SmKQ.DNCVHDLQAH
  374-  416 (43.42/19.57)	WSPTGPgtqnpnmnlILASASFDSTVRL..W.D.VErGACIHTLTKH
  425-  457 (49.80/23.32)	FSPDGK.........FLASGSFDKCVHI..W.S.TQsGQLVHSY.KG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26184 with Med16 domain of Kingdom Metazoa
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