<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26107
Description |
Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MNSLTVLNNIEDRVVESINTAGKALNILSKSLDIKQTTPSIQEFKQLSDRYFNIVEKDVYKGLMEFVDSMTDVAPFDHSSYSNKCELDVSHNFTEIILLHLEEMEEILKEDIN |
Length | 113 |
Position | Head |
Organism | Polysphondylium pallidum (strain ATCC 26659 / Pp 5 / PN500) (Heterostelium pallidum) |
Kingdom | Amoebozoa |
Lineage | Eukaryota> Amoebozoa> Evosea> Eumycetozoa> Dictyostelia> Acytosteliales>
Acytosteliaceae> Heterostelium.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.288 |
Instability index | 54.85 |
Isoelectric point | 4.50 |
Molecular weight | 12985.52 |
Publications | PubMed=21757610
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26107
No repeats found
No repeats found
|