<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26085

Description Uncharacterized protein
SequenceMPAVIEIVSLLEKVTITKELLETTRLGKHVNELRRKTDNDSLSKRAKELVKKWRNMVLPDSNGQLKPLEKRPLNRSPSPKRPKLNGQTAELELSDNSNSSFKDVISTKLKRDVILINSDSNSSQQEPQLEQQQPKKRGRKKGSKNHKNLLDEAETSFTNKLAVSRGNSKVKTTQELIAGLQNKNNTVLGASPVKPKEDLSLRAAKLTERVSIIDQKLNTNANRFKNSRKINLGGKNVIESGSVINDKSLIPPEEEVIVVDDVEPTVEDKPPETPPPEPPEEAKITSLSVEEALAQLPPLVVDEEEEPQPVCTCILKEHKDFSVDDTEELGQPFEFVEDEECAARLHFEGRKKTEEVTPEELHSKFIDNVNGNWGVGVAKMGPEVDDRGLFVNVVPNVNTESIPKDVKADFDCENYKKYSISESDRTGDRVFREWHEVVETPSYNGEIFKILPYVIID
Length457
PositionUnknown
OrganismTribolium castaneum (Red flour beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Tenebrionidae> Tenebrionidae incertae sedis> Tribolium.
Aromaticity0.04
Grand average of hydropathy-0.760
Instability index48.74
Isoelectric point5.36
Molecular weight51363.30
Publications
PubMed=18362917
PubMed=19820115

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26085
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.36|      17|      21|     293|     309|       2
---------------------------------------------------------------------------
  293-  309 (31.76/15.27)	LAQLPPLVVDEEEE.PQP
  315-  332 (25.60/11.08)	LKEHKDFSVDDTEElGQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.33|      12|      21|      59|      78|       3
---------------------------------------------------------------------------
   59-   73 (18.61/ 9.61)	PDSNGQLKPLEkrpL
   82-   93 (20.72/10.46)	PKLNGQTAELE...L
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.92|      18|      21|     159|     176|       4
---------------------------------------------------------------------------
  159-  176 (29.06/16.87)	NKLAVSRGNSKVKTTQEL
  182-  199 (30.87/18.35)	NKNNTVLGASPVKPKEDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.61|      20|      25|     351|     370|       5
---------------------------------------------------------------------------
  351-  370 (34.02/24.12)	KKTEEVTPEELHSKFIDNVN
  379-  398 (35.59/25.60)	KMGPEVDDRGLFVNVVPNVN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26085 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EEVIVVDDVEPTVEDKPPETPPPEPPEEAKITSLS
2) GKHVNELRRKTDNDSLSKRAKELVKKWRNMVLPDSNGQLKPLEKRPLNRSPSPKRPKLNGQTAELELSDNS
3) LINSDSNSSQQEPQLEQQQPKKRGRKKGSKNHKNLLDEAETSFT
4) SKVKTTQELIAGLQNKNNTVLGASPVKPKEDLSL
254
27
115
168
288
97
158
201










Molecular Recognition Features






MoRF SequenceStartStop




1) VKKWRNMVLP
50
59