<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26082

Description Uncharacterized protein
SequenceMVVCPADHGLQADIVFVIEGTAVNGAYINDLKTNYIIPSLEYFSQGSIDESSFLSEGINSYYGIVVYQAADCLPHPSSDTIGPFVSPSKVLNAIDKLELIGGKGESHANIAEGLATTLQCFDELQQKRDNNGNIQKHCILVCNSPPYSLGVFETHAYTGKTAEQLAAILQEKNINLSIISPRKIPSLYKLFEKAGGDLSASQTKNYAKDPRHLVLLRGFSLKERPLSPPAGTATSAQTQISNTTIPITSLPSPLASNDSPISSSSSANSGVPSGVGPSPVYRPPSAQGMVNARGAMMGNNPMNIPQLPAPPGYHQANRPRWPAMLPPTQPRSYLPPNQQVNTTQSSALIAQLTQPPNSMPGTGVNQFGQMGNNSPLNSQQQQPQMKINIMNQQNQQPNVQTSMSQNPNSGIQTTSIAQVSQPNQAGTSPGQSTPQPSQPLGPGRERPSIWQGLLEWIEKPKNPTDQQKITKHVPCQVSANSKDGEPELKADGWPSKLIMQLMPKQLIGNIGGAYLKNSKSVLFHPQPCEALESLTKVMSSGFAGCVHFTSTATPATCDIKVLILLYTAEKRAYLGFIPNDQGAFVDRLRKVIQQQKSTQIMRQTQGGAGQPMNPQTSGALTMGGTPPQMGGSNPVTSQTMMSQTNNMALGGGQITQNIVTSSAQAGILGQGPRLRMQQNIQQGMGPQSSQSAPNQNMAPGMMGTPPQRAPFENQLQVERQQNLEKINQLKQTLEAAQQQEQQYKSQLERISHMKTSQLQEALQICQQNEMKYKILDQQQRMANQNNPQAGSAQQQQRMMRPVMGANPGLRHLLQQQPQYRQQLMNMQQMAGNGPRPQMNQQMQNSGNNQQSGFDEVSYDFM
Length861
PositionUnknown
OrganismTribolium castaneum (Red flour beetle)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Coleoptera> Polyphaga> Cucujiformia> Tenebrionidae> Tenebrionidae incertae sedis> Tribolium.
Aromaticity0.05
Grand average of hydropathy-0.598
Instability index52.33
Isoelectric point9.05
Molecular weight93574.76
Publications
PubMed=18362917
PubMed=19820115

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26082
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.29|      21|      23|     315|     337|       1
---------------------------------------------------------------------------
  265-  285 (27.76/ 9.17)	SSANSGVPSGVGPS.P.VYRPPS
  315-  337 (30.52/19.50)	QANRPRWPAMLPPTqPrSYLPPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      95.27|      23|      23|     378|     400|       2
---------------------------------------------------------------------------
  370-  395 (35.28/11.81)	MGNNSplnSQ.....QQQPQMKINIMNQQNQ
  803-  828 (31.54/ 9.64)	MGAN....PGlrhllQQQPQYRQQLMNMQ.Q
  829-  848 (28.45/ 7.84)	MAGNG...P........RPQMNQQMQNSGNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     239.64|      49|      49|     702|     750|       3
---------------------------------------------------------------------------
  400-  433 (28.83/ 7.76)	............QTSMSQNPNS..GI....QTT..SIAQVSQPnQAGT..............spGqsT
  626-  670 (43.87/16.01)	PPQmggSNPVTSQTMMSQTNNMAlGGGQITQNIvtSSAQAG...................iL..G..Q
  671-  704 (40.59/14.21)	GP............RLRMQQN.......IQQGM....GPQSSQ.SAPN..Q....nmapgmM..G..T
  705-  755 (74.09/32.59)	PPQ...RAPFENQLQVERQQNLE.KINQLKQTL..EAAQQQEQ.QYKS..QLERI....shM..K..T
  756-  800 (52.27/20.62)	.......SQLQEALQICQQNEMKyKI..LDQQQ..RMANQNNP.QAGSaqQQQRM......M.....R
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.51|      18|      50|     102|     119|       4
---------------------------------------------------------------------------
  102-  119 (32.13/27.31)	GKGESHA...NIAEGLATTLQ
  150-  170 (26.38/20.92)	GVFETHAytgKTAEQLAAILQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.98|      25|      51|     514|     538|       5
---------------------------------------------------------------------------
  514-  538 (44.24/32.08)	YLKNSKSVL.FHPQPCEAL.ESLTKVM
  566-  592 (34.74/23.45)	YTAEKRAYLgFIPNDQGAFvDRLRKVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.09|      16|      24|     225|     241|      10
---------------------------------------------------------------------------
  225-  241 (24.83/16.16)	PL.SPPAGTAtSAQTQIS
  246-  262 (25.26/11.78)	PItSLPSPLA.SNDSPIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26082 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PLSPPAGTATSAQTQISNTTIPITSLPSPLASNDSPISSSSSANSGVPSGVGPSPVYRPPSAQGMVNARGAMMGNNPMNIPQLPAPPGYHQANRPRWPAMLPPTQPRSYLPPNQQVNTTQSSALIAQLTQPPNSMPGTGVNQFGQMGNNSPLNSQQQQPQMKINIMNQQNQQPNVQTSMSQNPNSGIQTTSIAQVSQPNQAGTSPGQSTPQPSQPLGPGRERPSIWQGLLEWIEKPKNPTDQQKITKHVPCQVSANSKDGEPELKADGWP
2) QKSTQIMRQTQGGAGQPMNPQTSGALTMGGTPPQMGGSNPVTSQTMMSQTNNMALGGGQIT
3) TSSAQAGILGQGPRLRMQQNIQQGMGPQSSQSAPNQNMAPGMMGTPPQRAPFENQLQVERQQNLEKINQLKQTLEAAQQQEQQYKSQLERISHMKTSQLQEAL
4) YKILDQQQRMANQNNPQAGSAQQQQRMMRPVMGANPGLRHLLQQQPQYRQQLMNMQQMAGNGPRPQMNQQMQNSGNNQQSGFDEVSY
225
595
660
772
494
655
762
858










Molecular Recognition Features






MoRF SequenceStartStop




NANANA