<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26081

Description Uncharacterized protein
SequenceMNQNQIQQLTSHLSQALDQNYDVVNMEAVLSVICALEGTTITKEQLEATRLAKYINQLRRRTKNDQLARRAKSLLKKWREMVGIHQQTTIEPQPQPLAHLSFKPIVGTHFPETESNTVEVMVNSTQYTSQSSPPSSQRGNPDLHPNVDSSEPHHINFSSLINNNINTDNRDDSLAIISKSIKHPRTIESKSQKSATFINEHSSNSVSSVMVANEKLNETSIVIDIVSDSDENDSQSQPVNNHQKLATVSSSLALPAVYPRPKKIKKDKKRKEKDEILSLSNSSMSSILSGDAFSGSSQNRPRTTAAELTFAGRFNSVSRPDTSNYVNAVQANGQKKICQVNDPPSLDLTIPQMYDDFINNDSSTSCSRLSPYEELEAKPGQNNSKASTEASKQQFLTSFKSNDSNKLECHENILSQAPKKRGRKKGSKGVDSLIAKESSLSQQILFGSGVKKVKTTKELFNDMQSRKLSISFNRGDSLPAVANKITNTTTLRNLESRSLIARPTSSCSETSIHSPHTLEAYSTNVSQAGTEKLSNILEEPGNTDSDTITSEPSRDSMKSRNIKRMNSLDSNSNSLQTTSVLTSSKDYNDVTTQLMHMVHNLNSPLSVNETEKLYQAQIVPCTCIVVEDIPKESSAHDNIDHSDMEADSINKATCDIETVRDKKHSEQPSLKTDNCDVEEAPLLISQKPIKSIFDLDFDDEDDPLQSIIKNISLPESNLKQDPDDYIKSSFTVRSLTEENKDLKVVSDSYLDQEASNIVLEPISVYTVYEDPDCVAKQRFDVQTNDVTNFHINALHNYYIPNINGNWNSIDSSIVLTTTVMKFLQSLESYTVTDGADVVPKYGSLTYERIRKDLSYLKFDRNWKSKSFKSFIPPFLGVAKCLPTCRLAAKRLKDKTKALSTTKSVETIIKLEEPEIIINYFEKNKGSPSPLRVEVDANGNSGENQAQTQSSEDDPLMNNNATLSFNLLKLVNNNEGRKSIVDDQVNSKPTIDGLDNRKGIRCSSDSSCSNSSLQLTQDSINEKLRNQRNLSLTSEQSQSERNVERNRKKRRKARHAESNDGIDFGNNIEIANTSIDEKPLIKRIKIAINGNVATQRQISGISSSNNSSDDEHDDEVGGEARSEVSDPEVGYNTSGYSQIGLAASDDEQESNRSHSTTIDSIAADDDGHLENEYENSNDEEYAIVQRPMVGVANNHIVLTIKKTPSKMNSPVNSISAISPNVGQASASVAGTLEAHTSKNAHFATTNTDSKIEYPETEIIGEYQRKFSLAPMVFCTDELHRLDPDRPFLTSNTCQNNLKTSYQYCRRRRRLRYRRPRDLICPKETIDIELKHLFNNVTRSTQMLLKPHRKLFFANELCRQDGAGRKERIVNYSSSSSSSSGSCTSNDEDDSDPEEKSKRERKRYSALSEDTEKCQIAVSKTQKLKNETDPNIAAKNINDQEDLYLYSDSDESLNTGEFGNQHNELNDPKLNKQDELPLHNNGMLPSFNFIYNDQQLKASANEVNEKAFEKPSLKLLQIQNCDDVNVCYNNINISVIKSHSLGSVKPINDDDNGKQCVINNLTSESLEKAKNCNPIYTDVSSELMLSQPAIEYRTGIRAVVDDAPSKYGVNTTQIQQFKEWHEVLQLQSYNNEPLIVLPYVVLE
Length1641
PositionUnknown
OrganismDrosophila virilis (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila.
Aromaticity0.05
Grand average of hydropathy-0.759
Instability index48.42
Isoelectric point5.62
Molecular weight183367.22
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP26081
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.82|      13|      28|    1272|    1285|       1
---------------------------------------------------------------------------
 1272- 1285 (22.43/16.73)	FCTDElHRLDPDRP
 1302- 1314 (26.40/15.11)	YCRRR.RRLRYRRP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     324.43|      88|     193|     250|     347|       2
---------------------------------------------------------------------------
  260-  324 (95.48/62.07)	.............................RPKKIKKDKKRKEK........DEI...LSL.SNSSMS.S..ILSGDAFSGSSQNRPRTTAAEL..TFAGR.....FN.SVSRPDTSN
  325-  401 (84.48/43.91)	YVNAVQANGQKKI.CQV.NDPPSLD..................ltipqmydDFInndSST.SCSRLS.P..YEELEAKPGQNNSKASTEASKQ..QFLTS.....FK.S........
  402-  483 (71.06/35.71)	.......NDSNKLeCHE.N......ilsqAPKKRGRKKGSKGV........DSL...IA..KESSLSqQ..ILFG...SGVKKVK...TTKELfnDMQSRklsisFNrGDSLPAVAN
  521-  590 (73.41/37.14)	YSTNVSQAGTEKL.SNIlEEPGNTD.........................sDTI...TSEpSRDSMK.SrnIKRMNSLD.SNSNSLQTTSV.L..TSSKD.....YN.DV.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     130.42|      33|      34|     661|     693|       3
---------------------------------------------------------------------------
  631-  661 (46.78/25.17)	KE.SSAHDNI....DHSDMEADSINKATCD...IETVRD
  662-  694 (55.37/31.32)	KK.HSEQPSLKT..DNCDVEEAPLLISQKP...IKSIFD
  695-  730 (28.27/11.94)	LDfDDEDDPLQSiiKNISLPESNL..KQDPddyIKSSF.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     222.93|      70|     518|     935|    1009|       5
---------------------------------------------------------------------------
  935- 1009 (111.23/87.58)	DANGNSGE........NQAQTQSSEDDPLMNNNATLSFNLLklVNNNEGRKSI..VDDQVNSKPTIDGLDNRKgirCSSDSSCSN
 1448- 1527 (111.70/73.99)	DESLNTGEfgnqhnelNDPKLNKQDELPLHNNGMLPSFNFI..YNDQQLKASAneVNEKAFEKPSLKLLQIQN...CDDVNVCYN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.28|      20|      29|    1186|    1205|       6
---------------------------------------------------------------------------
 1186- 1205 (34.88/25.13)	PMVGVANNHIVLTIKKTPSK
 1218- 1237 (33.40/23.73)	PNVGQASASVAGTLEAHTSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     257.04|      84|     832|       4|      97|       7
---------------------------------------------------------------------------
    4-   97 (115.88/120.15)	NQIQQLTSHLSqaLDQNYdvvNMEAVLSVICALEGttITKeQLEATRLAkyINQLRRRTKNDQLARRAKSLLKKWREMVGIHQQTTIEPQPQPL
  847-  930 (141.16/106.83)	ERIRKDLSYLK..FDRNW...KSKSFKSFIPPFLG..VAK.CLPTCRLA..AKRLKDKTKALSTTKSVETIIKLEEPEIIINYFEKNKGSPSPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.18|      16|      30|     781|     797|       8
---------------------------------------------------------------------------
  781-  797 (24.31/20.86)	VQTNDVTNFhINALHNY
  814-  829 (26.87/16.92)	VLTTTVMKF.LQSLESY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.50|      13|      28|    1536|    1548|       9
---------------------------------------------------------------------------
 1536- 1548 (24.32/15.60)	SHSLGSVK...PINDD
 1561- 1576 (18.18/ 9.55)	SESLEKAKncnPIYTD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP26081 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DDSLAIISKSIKHPRTIESKSQKSATFINEHSSN
2) DSDESLNTGEFGNQHNELNDPKLNKQDELPL
3) GTEKLSNILEEPGNTDSDTITSEPSRDSMKSRNIKRMNSLDSNSNSLQTTSVLTSSKDYND
4) RIVNYSSSSSSSSGSCTSNDEDDSDPEEKSKRERKRYSA
5) SPLRVEVDANGNSGENQAQTQSSEDDPLMN
6) SSLQLTQDSINEKLRNQRNLSLTSEQSQSERNVERNRKKRRKARHAESNDGIDFGNNIEIA
7) TESNTVEVMVNSTQYTSQSSPPSSQRGNPDLHPNVDSSEPHHINFSSLINNN
8) VATQRQISGISSSNNSSDDEHDDEVGGEARSEVSDPEVGYNTSGYSQIGLAASDDEQESNRSHSTTIDSIAADDDGHLENEYENSNDEEYAIVQR
171
1446
529
1366
928
1010
113
1091
204
1476
589
1404
957
1070
164
1185










Molecular Recognition Features






MoRF SequenceStartStop




NANANA