<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP26046
Description |
Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MLQITMYTTTPTHSSHTALTSSLQTLSASLQAVHTTAVAGAPPTPDGVPPNAQDQLGMPPGVPLHDPARHVTPGTLPNIPPELVQYVENGRNPDIYTREFVELVRRGNQLMRGKMGAFAQLRDVLAGEMRSAMPEVAEDVARVVEMTSPVKREGA |
Length | 155 |
Position | Middle |
Organism | Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136) (Verticillium wilt of alfalfa) (Verticillium albo-atrum) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Sordariomycetes>
Hypocreomycetidae> Glomerellales> Plectosphaerellaceae> Verticillium.
|
Aromaticity | 0.03 |
Grand average of hydropathy | -0.294 |
Instability index | 50.65 |
Isoelectric point | 5.91 |
Molecular weight | 16658.80 |
Publications | PubMed=21829347
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP26046
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 66.48| 14| 15| 77| 90| 1
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60- 74 (21.78/13.31) PGV.PlHDPARHVTPG
77- 90 (25.82/17.14) PNI.P.PELVQYVENG
93- 107 (18.89/10.58) PDIyT.REFVELVRRG
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 40.16| 12| 15| 111| 124| 2
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111- 124 (18.09/15.44) MRGKMGAFAQlrDV
129- 140 (22.07/12.09) MRSAMPEVAE..DV
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