<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25948

Description Uncharacterized protein
SequenceMQANKSPRVNWPQHENAVQGFSSRDGFLSSSFLFSLPTQKPSPEAPESMLSLRSSACKIQGSERFHAPLIEKAWRSLCNTQAARKSYLRPGLSAKVKDCDRGHARTCGEGSYNTNKMATVSGNRMPSVESTSQPTERISLQNNSSHQPVGISSSMRSYQSNHVAQEDTRATNQYNFARTDAALHQSAPVADNMCTYDNYDAMDDDILASIDVDRIVMEHYQATPRGSSHNMSTPPGNKCSFNGMDEANLPRELSELCSHQCKLAFCREAMTHLQEMKDELLAVANELLDDDGELNPQHSQELHQRRLHLKKLVQLLEDHMTRSAQDEERQISHSMASTKATQQHLPPMTPGSTFITDSNRFQSQVYIGNGPRDSDLCYSSAPYSCSDNLSTPLNSVWKSYTPKVIDINYTEGSGDRKWSSTNFPWTKDLEAKNRNKFGNRSFRPNQREIINATMSGYDVFVLMPTGGGKSLTYQLPALISVGLTLVVCPLVSLIQDQIMHLSQANIPATYLSGNLDWSEQQEIMRDLKSCRYKLLYVTPEKIARSGALSGLLRDLDSQGHLSRIVIDEAHCVSQWGHDFRPDYKELGVLKQNFPKTPVLALTATATARVKEDVVQALALENCIVFKQSFNRPNLRYYLRPKTKKCVEDIDMFIRENHYKECGIIYCLSRMDCEKVSEKLRECGHTVAHYHGSMDPVNRTRIQEDWSKDKINIICATIAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQPSSCLLYYQYSDYIRVRHMITQGVGEQTGAPRDLSSHEQALKTHKDNLLRMVSYCENDVDCRRLLQLIHFGERFDPSLCAKTCDNCLKESGWVEKDVTNIARQLVDLVTMTGHSNSSTHILEVYRGSVSQNVKKQRHDALPLHGAGKHLAKGEAARIMRHLVTEEILIEDVKKSDMYGSISSVLKVNHLKASDLRSGKRSVILKFPAPGKASKMGNLDTSLFPQINKTVQQQSEVDEKLASILYEALLTLRRQIMEECSEGCHAYHIFKTDTLKEMSIRVPRTKEELLDINGIGKTKLKKYGDRVLATIEDFLSKHPNPRRNISGSGGKEHSEAAKKRRGSTASSAVSCGDDDFEEPTGQSKKRAAKTRTVSDAASMVHGARCIDADLDGPEVVDVDEHCSVPKPVASGRVLPKWAPAKAKSKGSSVPPSNLFHEFGYAK
Length1195
PositionUnknown
OrganismSorghum bicolor (Sorghum) (Sorghum vulgare)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> PACMAD clade> Panicoideae> Andropogonodae> Andropogoneae> Sorghinae> Sorghum.
Aromaticity0.06
Grand average of hydropathy-0.576
Instability index48.33
Isoelectric point8.39
Molecular weight133707.83
Publications
PubMed=19189423
PubMed=29161754

Function

Annotated function 
GO - Cellular Component
chromosome	GO:0005694	IBA:GO_Central
cytoplasm	GO:0005737	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IBA:GO_Central
ATP binding	GO:0005524	IEA:UniProtKB-KW
four-way junction helicase activity	GO:0009378	IBA:GO_Central
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA duplex unwinding	GO:0032508	IBA:GO_Central
DNA recombination	GO:0006310	IBA:GO_Central
DNA repair	GO:0006281	IBA:GO_Central
DNA unwinding involved in DNA replication	GO:0006268	IBA:GO_Central
double-strand break repair via homologous recombination	GO:0000724	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25948
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.59|      31|      35|     133|     167|       1
---------------------------------------------------------------------------
  137-  167 (53.44/36.46)	RISLQNN......SSHQPVGISSSMRSYQSNHVAQED
  169-  205 (50.15/24.63)	RATNQYNfartdaALHQSAPVADNMCTYDNYDAMDDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.10|      14|      35|     801|     814|       2
---------------------------------------------------------------------------
  801-  814 (26.21/17.08)	DNLLRMVSYCENDV
  839-  852 (26.89/17.72)	DNCLKESGWVEKDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.27|      30|      34|    1080|    1112|       3
---------------------------------------------------------------------------
 1080- 1112 (49.54/45.95)	GSGGKehsEAAKKRRGSTASSAV...SCGDDDFEEP
 1114- 1146 (48.73/35.30)	GQSKK...RAAKTRTVSDAASMVhgaRCIDADLDGP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.49|      26|      34|     588|     613|       4
---------------------------------------------------------------------------
  588-  613 (41.25/24.79)	VLKQNFPKTPVLALTATATARVKEDV
  624-  649 (46.24/28.61)	VFKQSFNRPNLRYYLRPKTKKCVEDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.88|      12|      34|     741|     753|       5
---------------------------------------------------------------------------
  741-  753 (20.21/15.57)	EGYHQECGrAGRD
  777-  788 (22.67/12.23)	QGVGEQTG.APRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.30|      18|     141|     430|     448|       6
---------------------------------------------------------------------------
  430-  448 (28.92/21.09)	EAKNRNKFGnRSFRPNQRE
  568-  585 (37.38/22.78)	EAHCVSQWG.HDFRPDYKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     145.70|      47|     141|     874|     922|       7
---------------------------------------------------------------------------
  874-  922 (73.48/51.57)	HILEVYRG....SVSQNVKKQRHDALPLHGAGKHLAKGEAARIMRHLvtEEIL
 1018- 1068 (72.22/44.91)	HAYHIFKTdtlkEMSIRVPRTKEELLDINGIGKTKLKKYGDRVLATI..EDFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.24|      25|     141|     671|     695|       8
---------------------------------------------------------------------------
  671-  695 (45.88/37.76)	DCEKVSEKLRECGHTVAHYHGSMDP
  702-  726 (44.36/36.21)	QEDWSKDKINIICATIAFGMGINKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.56|      15|      36|     511|     525|       9
---------------------------------------------------------------------------
  511-  525 (28.61/18.49)	LSGNL.DWSEQQEIMR
  548-  563 (21.95/12.45)	LSGLLrDLDSQGHLSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.86|      21|      38|     274|     299|      14
---------------------------------------------------------------------------
  274-  299 (25.03/30.46)	QEMKDELLAVANellDDDGELNpqHS
  314-  334 (35.83/23.30)	QLLEDHMTRSAQ...DEERQIS..HS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25948 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSYNTNKMATVSGNRMPSVESTSQPTERISLQNNSSHQPVGISSSMRSYQSNHVAQEDTRATNQYNFARTDAA
2) HPNPRRNISGSGGKEHSEAAKKRRGSTASSAVSCGDDDFEEPTGQSKKRAAKTRTVS
3) LEDHMTRSAQDEERQISHSMASTKATQQHLPPMTPGSTF
110
1071
316
182
1127
354










Molecular Recognition Features






MoRF SequenceStartStop




1) GRVLPKWAPAKAKSKGSSVPPSNLFHEFGYAK
1164
1195