<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25920

Description Uncharacterized protein
SequenceMNIPPNQNPLQMGGTSSSWQGMYSGEERQKVVQIIINTLTELNGTNPNFNQQRLAKMASDFEKIVYEKSPSKEDYLRAIKIKVHQLRLQKQQMAANQGGQSINPQQQQQQQQQQQQVPPPQQQQQQQAQRGNNNMNQMNSQNLQFLQQQAQARSQSQAQIQARQQQLRNMVNQQQQAQQSQQQQQQVPQPQQQQQQQPQQQPSQQPQPQQNQQPGGGQAPPPTQNQLPPHLVNLMRTSPIPPPLLNKMPKLPNGVNTWNQIFDLIRKEIIPRDMVPAIRDIHGMHLQLFMRQQQQKMNMQRNMNEGPVNNNDNSAMQSNLNNNNNSNNNMMGNMPPNFNNLTPQQREQILRQRRLQQQQMQQQKQANQPQVPQTQPPQQTQQPQPQQQVQSQQQGPQQMPQPMVQQNQNPQMGQSSNMQQQNIPPNQQRPPQFQVTAEDYAKYNNDALLFLSKLSQQKQWPAQIDESMKEQFIKKFIIHQKTQQWKQQQMQQQQQRGNTNNLGMNTGTSAAPPPQAQPQSQSQPSQQQPVGQMPMQPQVNLQNQQQQQTSQNGPQAQVQQPIPGMVQGSPVMSNMATPLMKPNTQLNANNVSSPLMGQRMNMNNANANANANANAAMPPAGNNNNNNNNNRVRPVTAPANINMSSIIPPLTDEVKLRLRQLIEEVSRNNVVLRDVTNLLSPQDKTTVRESMNQIQEQYGNVDSVISYFYLLTKNGDGTKRLIQMKYMTKNILDNLHRGIYLAGPDLLEKVKSQYAKYFDYVREQINMRRQQALQQAAGGAPQQQQSQQQVPPPQQQSQPQQGMPRSQPPQGQQPMMQGQVRNQQFMNQNPQIAMQQQQQQQQQQQQPMMGQHDQMNMKNWSPVPGAGPNQMNMNSQQAPQQQQLRQGINSSPLMPQQLTPMQQQQQLPPQPQPPQPSQQHQQMPGPPQMPMQPQPQPPIAKPTTAAAQKTAAKTTAKKGTQGRKKSKANNSAPTPAALPAATPGTLANAIKTPHSIPTPQIPPQSHSNKNTPSAHSPAYPVKATPSGTTPGTGSFSNVNSNNVYPTPEIDVFAMSSNDSKVAKRRELLNTDPEKFFYASLANLLDLDESVVDNVKVSPRMSNGKPIANSPLSPKISGEWTSEVKPMAITTSFRQVDAIKDLTNDDIISSCGMLAIQEVEEPKQLKREREQEDELDTLFNDKKLKLTDGNNFDKFLYEPSSFDEWKDFVVSFIQ
Length1213
PositionTail
OrganismCandida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.04
Grand average of hydropathy-1.123
Instability index73.82
Isoelectric point9.82
Molecular weight136966.00
Publications
PubMed=19465905

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25920
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     444.25|      65|      67|      87|     152|       1
---------------------------------------------------------------------------
   87-  152 (123.06/25.35)	RLQKQ...QMAANQGG..QSINPQQQ.QQQQQQQQQVPPPQQQQQQQAQR.......GNNNMNQMNSQNlQFLQQQAQA
  153-  205 (64.61/ 7.38)	RSQSQ..aQIQARQQQlrNMVNQQQQaQQSQQQQQQVPQPQQQQQQQPQQ.......QP.......SQQ..........
  354-  405 (78.60/11.29)	RLQQQ...QM..QQQK..QANQPQVP.QTQPPQQTQQPQPQQQVQSQ.QQ.......GPQQMPQPMVQ...........
  769-  814 (86.46/13.60)	RQQAL...QQAA..GG.....APQQQ.QSQQQ....VPPPQQQ..SQPQQ.......G...MPR..SQ....PPQGQQP
  815-  884 (91.53/15.01)	MMQGQvrnQQFMNQNP..Q.IAMQQQ.QQQQQQQQQ.PMMGQHDQMNMKNwspvpgaGPNQMN.MNSQ..QAPQQQ.QL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     102.15|      22|      22|     583|     604|       2
---------------------------------------------------------------------------
  317-  336 (37.69/15.20)	QSNLNNNNN.........SNN.NMM.G.NMPP
  596-  619 (34.09/12.98)	MGQRMNMNN........aNANANANaNAAMPP
  620-  650 (30.37/10.69)	AGNNNNNNNnnrvrpvtaPANINMS.SIIPPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     464.79|      80|     394|     513|     594|       3
---------------------------------------------------------------------------
  206-  305 (84.81/16.62)	....P..QPQQNQQPggGQA.PPPTQNQLPPHlVNLM.....RTSpipppllnkmpklPNGvntwnqifdlirkeiiPRDMV.......................PAIRDIHGMHLQLFMRQQQ.QK.....MNM....QRNMNE
  406-  483 (55.36/ 7.16)	..............Q..NQN.PQMGQSS......NMQQQNIPPNQ.............QRP................PQFQVtaedyakynndallflsklsqQKQWPAQIDES.....MKEQF.IKkfiihQKT....Q.....
  513-  590 (138.10/33.72)	...PPQAQPQSQSQP..SQQ.QPVGQMPMQPQ.VNLQNQQQQQTS.............QNG................PQAQV.....................QQPIPGMVQGSPVMSNMATPL.MK.....PNT....QLNANN
  905-  970 (95.92/18.90)	QQlPPQPQPPQPSQQ..HQQmPGPPQMPMQPQ.P......Q....................................PP..I.....................AKPTTAAAQKTAAKTTAKKGT.QG.....RKK....S.KANN
  972- 1042 (90.60/17.87)	AP.TPAALP........AAT.PGTLANAIKTP.HS.....IP.TP.............QIP................PQSHS.....................NKNTPS..AHSPAYPVKATPSgTT.....PGTgsfsNVNSNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.54|      16|      30|     694|     710|       4
---------------------------------------------------------------------------
  702-  730 (15.38/10.34)	DSVISYFYLltkngdgtkrlIQMKYmtKN
  733-  756 (19.16/ 7.98)	DNLHRGIYL...agpdllekVKSQY..AK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25920 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




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
2) RRQQALQQAAGGAPQQQQSQQQVPPPQQQSQPQQGMPRSQPPQGQQPMMQGQVRNQQFMNQNPQIAMQQQQQQQQQQQQPMMGQHDQMNMKNWSPVPGAGPNQMNMNSQQAPQQQQLRQGINSSPLMPQQLTPMQQQQQLPPQPQPPQPSQQHQQMPGPPQMPMQPQPQPPIAKPTTAAAQKTAAKTTAKKGTQGRKKSKANNSAPTPAALPAATPGTLANAIKTPHSIPTPQIPPQSHSNKNTPSAHSPAYPVKATPSGTTPGTGSFSNVNSNN
87
768
644
1042










Molecular Recognition Features






MoRF SequenceStartStop




1) AAQKTAAKTTAKKGTQGRKKSKA
2) KKFII
946
474
968
478