<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25919

Description Uncharacterized protein
SequenceMSADYWNSSQRNQWQLTRFSLLEARRKVLLLERKMIQNGLIKDYPNIIYDYNMRIYLHNLLIKLGRRLNIRQLALATAEIYLTRFLTRVSIKEINVYLLITTCLYVACKIEECPQHIRLIISEARNIWPEYIPHDVTKLAEFEFYLIEEMDSYLLLHHPYKSLIQIRDFLKNNYANYGFKLTEEELQNAWSLINDSYITDVHLLLPPHTIAIAAIYITIVLKKNLSHLRQSNNNSNSNTAVSSSAVNNNNNSGSNSNNNGGGNTVTNNTTNNTTTSTGESNEENGKEMNIDDLMNLTKVTNTKLGDDKMDIDSTNNGQQSQSETQNQNQQTNTDQLNNFDLDILDEDTIKINKFMNFLEHSHINLDEVVEAVQDMMNMYVLWNRYNEQGVKKALQVMLLNRM
Length402
PositionKinase
OrganismCandida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.08
Grand average of hydropathy-0.490
Instability index42.08
Isoelectric point5.63
Molecular weight46589.08
Publications
PubMed=19465905

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:EnsemblFungi
GO - Biological Function
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	IEA:EnsemblFungi
RNA polymerase II core promoter sequence-specific DNA binding	GO:0000979	IEA:EnsemblFungi
GO - Biological Process
negative regulation of transcription by RNA polymerase II	GO:0000122	IEA:EnsemblFungi
positive regulation of transcription by galactose	GO:0000411	IEA:EnsemblFungi
positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	GO:0010673	IEA:EnsemblFungi

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP25919
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.25|      18|      23|     230|     252|       1
---------------------------------------------------------------------------
  233-  250 (30.39/17.36)	NNSNSNTAVSSSAVNNNN
  267-  284 (30.86/ 6.41)	NNTTNNTTTSTGESNEEN
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP25919 with CycC domain of Kingdom Fungi

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LRQSNNNSNSNTAVSSSAVNNNNNSGSNSNNNGGGNTVTNNTTNNTTTSTGESNEENGKEMNIDDLMNLT
2) NTKLGDDKMDIDSTNNGQQSQSETQNQNQQTNTDQLNNFDLD
228
301
297
342

Molecular Recognition Features

MoRF SequenceStartStop
NANANA