<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25916

Description Uncharacterized protein
SequenceMSTNKSRNRNSLLSSHSRSSYSNSNTKDEIIAMKYSMDKPDLPIYPMSDHMQKNSSTDVKTNQNHEKSEQIYPDFMPWKDHTQLSTDQQEKQHQRLNNASYLNKGYFEAPQVANEYYSARNLISATVFLSNDNCNTVVKELSTYLTNAYKTRNEVINKIKYDSNHFKIPNRVTLTSNKKEAWLREISNYNVPLKKIGEKIPHGLRNKVLIDAICTRGVPINRSIWLTKCVLYGELVSLRRKHQNRMSVSGTIPSVNDFNTFEKFEVHWLQEWTQQVADYVLKFSREMSSINSTEKKAQYLRKFNHLINYVKSLYVESLLDKSFFLSSVLRFLKDGLPLQPKHIDQLLSISTDDNNRSMSSGNDSGDGDDDNDDDYDDNELAGKQNSWIHDVDMNYGQRLAALTLIKVFWNDLIKVDYLSKELSELLLLNYFFIERWSTSPTTSATYEKFGLSDGLRFKILKLITDTVKYLFEFNCNIFIIPNYWMLIESSLVKILLNSFKEGGSEKEHEQILKQLELIKYRNESLILNMKNEANVNSENNRLINRSASFSGFNSTAVSPAPSSNVETDYTFINRNSDDILNIIEKLDTLRFNEEFSNLLKPGRKGNKNWQLNLKVVLCWCVSPSRDYRDSIGDILFICNFLRNNVSADLNKSLKAEFDNEILEIIYQIAEDTTSNFVNANLYVLINELYQLKLITIAAYLRKLIASGIFYLEPGTHQDLNNLPLVARTHLEILENLPVLNNRQCDSILKKWTPSGFDFKGKFTDGQAMLQKSIIDKVFSNSLNRHENTECTNYISSLNVGLQFLLINWLTNEIKSKSSSAVRLIHFTPAVVTSLYQFYSQTAGLTVFFKVLIPTILKNDGGMIIFYLDTLFLISKLTVRHFKLIKFIPGGYDSPCIGYDIFKLIVQAYKDLCGREYDYFRFDNLWNFMDAVIEKAPENSHTNEGFSNSEQSLPKLPNSLTGKDTLESPMHINTVEIPAARSHAETRSGSRRYTSTDFRNDISYLRGLVLQPLTPEDSDEIRAMFETDIIGTELQYWYDNFENLSEEKEIALVKLLRSILVSDQSFTTKIREFLVESVKNSTDSQRLTTFLMKMNVYDITRMNELVKTLLPVCSESGQESIVDELVLGTEGIENRVLSISQKVLLELNRHFYRVRSIKSYSMIISRGLLKGGPAFSNAFFVKYRIPILRFLNLAIVTNTKSILNELYIKLPREDCLELLNIQLGRTEDNFIKTLGDFEKFIPEIDEFNLPVCQILLGVISNSLVPLDFSMVKEQLEHFMNVLLSTMNLRFSNSNSFFGELFSFMAWTHKICILEILETKFLTETKFDNGIELFVTPTSQQNLLPSLNDFLKKFAASSSSSANSVESDKNLLQKLLEFIDKLVAVVNSEEVVEPTDSISCAISVFLRILIIHKSSLCEYISIWTTDQLVISFVSKLIDLLNSKYLSNSDDKLRILLYDLLLLMKSGITQEMHSTRDTELSDSTSPQHHVNEPLKQQQAKDIEHEATSPKSKDSKLENVHIVSSIQSLFDLPEPSTANPFAAYLNDSLVKCSLMLDNDELERGGDISVFNNRGLVLKSTRNESSELTSFGENNIMKSKNQQVKDFKFKSFEILEDIGTNSLNDGCINLQLFDAYTTRENPP
Length1638
PositionKinase
OrganismCandida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Candida.
Aromaticity0.10
Grand average of hydropathy-0.300
Instability index40.72
Isoelectric point5.78
Molecular weight187824.56
Publications
PubMed=19465905

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25916
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     288.86|      87|      96|     943|    1032|       1
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  536-  579 (44.39/26.27)	....N.SEN.........NR.LINRSASFSGFNSTAVS.PAPSSNVETD......YTFINR.NsdDI.................................
  943- 1032 (140.57/118.26)	EGFSN.SEQ...SLPKLPNS.LTGKDTLESPMHINTVEiPAARSHAETRSGSRRYTSTDFR.N..DISYLRGLV..LQPLTPEDSDEirAMFETDIIGTE
 1038- 1129 (103.89/76.10)	DNFENlSEEkeiALVKLLRSiLVSDQSFTTKIREFLVE......SVKNSTDSQRLTTFLMKmNvyDITRMNELVktLLPVCSESGQE..SIVDELVLGTE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.04|      46|      96|    1186|    1231|       2
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 1186- 1231 (72.57/41.24)	ILRFLNLAIVTNTKSILNEL..YIKLP....REDC.LELLNIQ.LGRTE.DNFIK
 1242- 1283 (42.22/20.97)	EIDEFNLPVCQILLGVISNS..LVPLDfsmvKEQL.EHFMNVL.LS.........
 1285- 1330 (44.25/22.33)	....MNLRF.SNSNSFFGELfsFMAWT....HKICiLEILETKfLTETKfDNGIE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.99|      53|     100|    1442|    1498|       3
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 1442- 1498 (79.13/67.96)	YLSNSDDKLRILL........YDLLLLMKSGITqeMHSTRDtELSDSTS.PQHHVNEPlKQQQAKD
 1540- 1601 (78.86/52.17)	YLNDSLVKCSLMLdndelergGDISVFNNRGLV..LKSTRN.ESSELTSfGENNIMKS.KNQQVKD
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.90|      60|      98|     184|     249|       4
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  184-  249 (99.02/78.35)	REISNYNVPLKKIG..EKIPHglrnkvLIDAICTRGVP..INRSIWLTKCVLY.GELVSLRRKHQNR.MSVS
  285-  350 (82.87/53.65)	REMSSINSTEKKAQylRKFNH......LINYVKSLYVEslLDKSFFLSSVLRFlKDGLPLQPKHIDQlLSIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.28|      28|     309|     141|     170|       7
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  141-  170 (45.78/31.47)	LSTYLTnaYKTRNEVINKIKY....DSNHFKIPN
  451-  482 (44.49/24.65)	LSDGLR..FKILKLITDTVKYlfefNCNIFIIPN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.08|      36|     550|     839|     876|      10
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  839-  876 (56.17/48.09)	SQTAGLTVFFKVLIptILKND..GGMIIFYLDTLFL..ISKL
 1395- 1434 (51.91/36.48)	SISCAISVFLRILI..IHKSSlcEYISIWTTDQLVIsfVSKL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.18|      31|     617|     736|     771|      15
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  736-  771 (50.58/40.38)	LPVLNNrqcdsILKKWTPSGFDFKGKFTDGQAMLQK
 1342- 1372 (50.60/28.57)	LPSLND.....FLKKFAASSSSSANSVESDKNLLQK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25916 with Med12 domain of Kingdom Fungi
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