<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25871

Description Uncharacterized protein
SequenceMPASARFALELEFVLSLANPHYLSHLAVAHPHLLGITQASTRGREQDRSREESRAFAAYLAYLYDYWRRPEYVQFLTHPGATLRALRLLQEEAFRLAVIRPQACRPKHQVLVLKCYPRFQKGVQVVRPNSSELSYLLYYASTRRSKLQKVGAFLEKRAARDVWRQKLGNVQVTMQLLAALIEKLPRDLPLYACSVLAILDTVLQHSDDIAMVEETIPTFQALCSHQDAAALAADAHYTSQYRDLVRRYAALASPAAHASLAAPMALRWRNVGLQAVRSVVASEALGADWSRQLSIVIPVVLQSLYHHDDDDDPGLLPLQQRALSSQSHEREHARRRRMSIATVQTVDTVDGNPESAAGTAADADKAAETEAQVLALRCLEKIFTPGSNRMQIRLATALVLDFIVARNPPRKAGRGSSNWATDLLEVIVNWTPVQDRFVLLVTLVEALAERPLVDGQLEPQLTLVYMIEWLLSSPINLIGLSVMDVLIALLRYLVLLLHLGDGRATVVPPPSNTAFALPAGSSPSVDAAAATTTTTTTTTTTSRPASMRQELLLLLQSSVANLANHVYYTDQISDMIRTILSHIKPVSSTSTTSDDSEKPESVVTDTYFSTPTAQLIALKAAKDTLVAANARQTTGAAVGNAAGAATDSRHRVPVQAWEGSQWLLRDADREVRHAYVDALLCWLRLETNESDLRAPAEPLKVAKKRERDVAEKLARRALGQDDRQAASEDSRFLQHLHFTVYEIATDQSAAEADVMLVHLLMVHLVERLGVNAVRYGLPVMIKVQSHSLDASSPSSPLRAGSLVHGYLSAVVEKFTLEGTKVGGEILNEVVRRKRNGLWLSKIQLPPLPATRTLAEQALNASESNAAQSDRTAYVPFTSLAELVSQIETAYGQSCLSPPSSPAGSPNAGQGHAVLSSSSSQARHPQTTQLPQHIKEQMLAPWSREACLASIEQERTRSSSLAGSKNGSAAARNHLNIAAGKNATASSPTGTDSSHGKWHRPVSASAAAVSRGESRKDRRQSLTEVPHPRSPTTASSSKDSTVRVNELRRVLSVVNNSNVRHPSPLRGHSRLGSDADASSAESMVTDTFSTSDAGFSSIGPAGTAGAVLEKVQLVHTQPTASSRSDGHPEDDIPPVPPIPAVSSSSSTRQPRRQTTSTSKTRESRSHSRPRSKSRTRTPSASRRASSPQPSTRSRKHSRSAADAHGEGHQNRRAEVDKLLDGIAAPGEREHGYEAGLIPGADTTTMSRSLFAPTNSRASSTRRGIGPPPY
Length1268
PositionMiddle
OrganismArthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Onygenales> Arthrodermataceae> Microsporum.
Aromaticity0.05
Grand average of hydropathy-0.326
Instability index57.57
Isoelectric point9.41
Molecular weight137760.73
Publications
PubMed=22951933

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
protein localization to plasma membrane	GO:0072659	IEA:InterPro
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25871
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.38|      22|      24|     961|     982|       1
---------------------------------------------------------------------------
  961-  982 (34.66/15.83)	AGSKNG..SAAARNHLNIAAGKNA
  984- 1007 (36.22/16.86)	ASSPTGtdSSHGKWHRPVSASAAA
 1183- 1200 (27.50/11.09)	ASSPQP..STRSRKH...SRSAA.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      62.73|      12|      31|    1024|    1035|       2
---------------------------------------------------------------------------
  830-  841 (17.25/ 6.05)	VRRKRNGLWLSK
 1024- 1035 (23.15/11.14)	VPHPRSPTTASS
 1058- 1068 (22.33/10.43)	VRHP.SPLRGHS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     320.10|      89|     125|     143|     235|       3
---------------------------------------------------------------------------
   65-  137 (82.56/48.98)	..................DY.......WRrpeyvQFLTHPGATLRALR..LLQEEAFR.........LA.VIRPQACRPKHQVLVLKCYPRFQkgVQVVR...........................PNSSELSYLL
  143-  235 (137.67/97.37)	RRSKLQKVGAFLEKRAARDV.......WR.....QKLGNVQVTMQLLA..ALIEKLPRDLPLyacsVLA.ILDTVLQHSDDIAMVEETIPTFQ..ALCSH...........................QDAAALAADA
  241-  363 (99.87/61.01)	YRDLVRRYAALASPAAHASLaapmalrWR.....N.VG.LQAVRSVVAseALGADWSRQLSI....VIPvVLQSLYHHDDDDD..PGLLPLQQ.rALSSQshereharrrrmsiatvqtvdtvdgnpESAAGTAADA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     204.34|      51|     287|     908|     960|       5
---------------------------------------------------------------------------
  908-  960 (89.75/54.22)	GQGHAVlsSSSSQARHP..QTTQLPQHIKEQMLAPWSR....EACLASIEQERTRSSSL
 1139- 1180 (51.83/25.21)	....AV..SSSSSTRQPrrQTTSTS...KTRESRSHSR....P...RSKSRTRTPSAS.
 1204- 1248 (62.76/32.12)	GEGH........QNRRA..EVDKLLDGIA....APGERehgyEAGLIPGADTTTMSRSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.57|      14|     136|    1117|    1136|       6
---------------------------------------------------------------------------
 1117- 1136 (20.42/24.74)	PT...ASSRSDGhpeddIPPvPP
 1251- 1267 (25.16/11.19)	PTnsrASSTRRG.....IGP.PP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.39|      25|     138|     713|     739|      10
---------------------------------------------------------------------------
  713-  739 (38.43/33.62)	LARRALGQDDRQAASEDSrfLQHLHFT
  853-  877 (41.96/28.68)	LAEQALNASESNAAQSDR..TAYVPFT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25871 with Med31 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EACLASIEQERTRSSSLAGSKNGSAAARNHLNIAAGKNATASSPTGTDSSHGKWHRPVSASAAAVSRGESRKDRRQSLTEVPHPRSPTTASSSKDSTVRVNELRRVLSVVNNSNVRHPSPLRGHSRLGSDADASSAESMVTDTFSTSDAGFSSIGPAGTAGAVLEKVQLVHTQPTASSRSDGHPEDDIPPVPPIPAVSSSSSTRQPRRQTTSTSKTRESRSHSRPRSKSRTRTPSASRRASSPQPSTRSRKHSRSAADAHGEGHQNRRAEVDKLLDGIAAPGEREHGYEAGLIPGADTTTMSRSLFAPTNSRASSTRRGIGPPPY
2) SCLSPPSSPAGSPNAGQGHAVLSSSSSQARHPQTTQLPQHIKEQML
944
893
1268
938










Molecular Recognition Features






MoRF SequenceStartStop




NANANA