<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25827

Description KLTH0E11396p
SequenceMYGIQNKPPNDYPIPIQQQSSQNIWQQQMVDNKGSTSASGKPLLMANNNVFSIGPYKRRKDANRVSVVEKYEIIGYIAAGTYGKVYKAKRKLQNPSSSTTSLVGSEVANTTSNNPISDHNILDTNSINKTTRVQDASSGLPQASSIDFSKSEAKSSHTLPGGQEPQAGGVPDGSMMVSSNDNLPTLFAIKKFKTEREGVEQLHYTGISQSACREMSLCRELRNKHLTSLVEIFLENKSIYMVSEFAEHDLLQIIHFHSHPEKRLIPPRMLKSIVWQILDGVSYLHQNWILHRDLKPANIMVTVDGCVKIGDLGLARKFHNMVQTLYTGDKVVVTIWYRAPELLLGARHYTPAIDLWAVGCIFAELIGLRPIFKGEEAKMDSKKSVPFQANQLQRILEVLGSPNEKTWPNIFKYSEYEQLSKFPRYRDNLPVWYHSAGGRNKEALDLLYQLLRYDPVTRIDAVDALEHPFFTNEDPTVCENVFEGLNYQYPPRRIHTNDNDIMNIANNKAKNTAVHAQVMASNNPNNSNLGGLGVNRRILAAAAAAAAAVSGNNSSMRPGAASSSNGPARKKRG
Length573
PositionKinase
OrganismLachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Lachancea.
Aromaticity0.08
Grand average of hydropathy-0.459
Instability index44.25
Isoelectric point9.21
Molecular weight63793.66
Publications
PubMed=19525356

Function

Annotated function
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP25827
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.02|      20|      21|     140|     160|       1
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  141-  160 (34.13/23.37)	PQASSIDFSKSEAKSSHTLP
  165-  184 (36.90/20.66)	PQAGGVPDGSMMVSSNDNLP
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.80|      18|      19|      94|     111|       2
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   94-  111 (29.38/22.31)	NPSSSTTSLVGSEVANTT
  114-  131 (31.42/24.41)	NPISDHNILDTNSINKTT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.84|      20|      21|     252|     271|       3
---------------------------------------------------------------------------
  252-  271 (37.99/26.63)	QIIHFHSHPEKRLIPPRMLK
  276-  295 (36.86/25.62)	QILDGVSYLHQNWILHRDLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.77|      18|      19|     503|     520|       4
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  503-  520 (28.81/17.68)	NIANNKAKNTAVHAQVMA
  523-  540 (29.97/18.67)	NPNNSNLGGLGVNRRILA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.67|      13|      34|     451|     463|       6
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  451-  463 (23.77/14.27)	LRYD.PVTRIDAVD
  485-  498 (21.90/12.62)	LNYQyPPRRIHTND
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP25827 with CDK8 domain of Kingdom Fungi

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