<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25799

Description Uncharacterized protein
SequenceMNNLGNGPMGGTWHSTYGISDRQKVIQILSTTLKEIQNGHYDEQKAATMAQEFEKYTFMKSASREEYLRMIKQKVTQLRSGLMNNPNAQMASNVGPPQNDMGLQNGNFYNQGRQQMSPMRNNLVPQQQQHQQHQQQQQQQQQQQQQQQPQQKQQSQPQQQQQQQPNRLSRSQPSASQSLQPTQQQIQQISFMIRTVPIPPALLAKVPNLPPNVNTWTQIYDCFQKKIIPASAMPIIKEIHNAHFQHALRQHQQQKLLQLQRMNNTAGNDGVGQLGGENNQSLGSAGNFSASMNNMGNMNNVSVMNNMGNMNMNTANNMGNMTNMGNMNNMGNISNAGNMANMGNMNNMNNMKMNNMNNLGGMNNMSMKNVNNSNNMANMGNVAGGMSNMGNMAMNDVNRQIPRNAMGAHGPQIQQQNGYVGVNKAQNSQNQQQQQQQQQQQPAGRVQMPQAKQQQQISTPASNQAIPVGQQQQAAKTPNIQITSQDLLKYNSDAMALLGRLQANGSISPNLDQAQKQNFVRKYIYHQKLSLWKAQQKASAINNPMNLPQSQPAPLQQAQVPPSSMGQGGFPQAPIQSQPQQQQQQQQPQQPQQLQQPQGQRRPRSSPVMQQPVPASAMNQQMYAQNMQQKSAPVQAANPVPQVRPAPLALAGGMPPLTDEMKMKLRSLFEEVSRNNVQLKDVTMLLSEKDKAQVKETMARISQQYANVDSVLSYFYVLTRNLEGTKRLIQMKHMTKSIMENLQRGIYLAGPDLLEKLRSQYQRYFEYVKEQITLSKQQQQQQQQQHPPNRPQNEPIPQRMNQMGPQGHFPTNPPGVQHNVVPHSQPVFNAQGVSGQMGIPQSQQQQQQQQQHFARNSVSAPIPQQEWQNNSGTMASQNNPLASSPNMPQAGSPLQAPPQAVGKSGAKVPTKKNIAAGNRRRSTKGAGTPAAGAPTPASLANAIKTPHSISTPQMPPAQSNKGTPMGVSPNSEAKLAAQNEQMPFGGEMFGANGMDSDLMKRRELSKTNPKEFFFAALSNLLDISDDEQDKGSGGTSAGNGSTTELKALTQSPLSPSNTGRWNCDVKPHAIASAFCQVNVIKECSGPSILDECARIVELGASAPTKNGIKRERNEDDDIDLLFDEKKVKVEDSNNPSKRMYEPLEYDEWVTWFKGLQETRV
Length1160
PositionTail
OrganismClavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora.
Aromaticity0.04
Grand average of hydropathy-0.919
Instability index63.75
Isoelectric point9.75
Molecular weight128610.21
Publications
PubMed=19465905

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25799
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     102.14|      15|      15|     319|     333|       1
---------------------------------------------------------------------------
  300-  322 (22.69/ 6.84)	NVSVMNNMGNMnmntannmGNMT
  323-  340 (28.61/10.72)	NMGNMNNMGNI.....snaGNMA
  341-  357 (29.00/10.97)	NMGNMNNMNNM......kmNNMN
  372-  387 (21.84/ 6.28)	NSNNMANMGNV.......aGGMS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.86|      15|      15|     135|     149|       2
---------------------------------------------------------------------------
  135-  149 (33.54/ 7.56)	QQQQQQQQQQQQQQP
  151-  165 (31.17/ 6.53)	QKQQSQPQQQQQQQP
  428-  442 (32.15/ 6.96)	SQNQQQQQQQQQQQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     151.99|      31|      31|     549|     579|       3
---------------------------------------------------------------------------
  563-  591 (46.46/13.22)	SSMGQGGFPQAPIQSQ.....PqqqQQQQQPQQ.....P
  592-  615 (37.15/ 8.73)	QQLQQ...PQG..QRR.....P.....RSSPVMQQPVPA
  789-  823 (32.33/ 6.41)	NRPQNEPIPQRMNQMGpqghfP....TNPPGVQHNVVPH
  872-  898 (36.05/ 8.20)	GTMASQNNPLASSPNM.....P...QA.GSPLQA...PP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.13|      25|      64|     762|     786|       4
---------------------------------------------------------------------------
  762-  786 (40.04/10.96)	QRYFEY..VKEQITLSK.QQQQQQQQQH
  825-  852 (38.08/10.07)	QPVFNAqgVSGQMGIPQsQQQQQQQQQH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     220.85|      36|      92|     527|     562|       5
---------------------------------------------------------------------------
  179-  214 (38.22/10.53)	LQP.....TQQQIQQISfmiRTVPIP...PALLAK...VPnlPPNVN
  215-  255 (46.08/14.09)	TWTqiydcFQKKIIPAS...AMPIIKEIHNAHFQHA.LRQ..HQQQK
  498-  530 (45.79/13.96)	LGR.....LQANGS.IS....P.NLDQAQKQNFVRK.YIY..HQKLS
  531-  562 (50.72/16.19)	LWK.....AQQKASAIN...NPMNLPQSQPAPLQQA.QVP..P....
  624-  656 (40.03/11.35)	AQN.....MQQKSAPVQ...AANPVPQVRPAPLALAgGMP..P....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.53|      10|      24|     362|     371|       6
---------------------------------------------------------------------------
  362-  371 (20.47/ 8.82)	MNNMSMKNVN
  389-  398 (20.06/ 8.51)	MGNMAMNDVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.09|      27|      44|     400|     426|      10
---------------------------------------------------------------------------
   97-  124 (25.14/ 6.55)	..PQNDMGLQNGNFynQgrQQMSPMRNNLV.
  400-  426 (48.80/21.17)	QIPRNAMGAHGPQI..Q..QQNGYVGVNKAQ
  447-  464 (33.15/11.50)	QMPQ......AKQ...Q..QQISTPASN..Q
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.46|      14|      22|     902|     915|      11
---------------------------------------------------------------------------
  902-  915 (23.74/15.71)	GKSGAKVPTKKNIA
  927-  940 (24.73/16.75)	GTPAAGAPTPASLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.03|      13|      22|     266|     278|      13
---------------------------------------------------------------------------
  266-  278 (23.84/10.86)	AGN..DGVGQLGGEN
  285-  299 (20.20/ 8.03)	AGNfsASMNNMGNMN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      55.74|      18|      55|     666|     683|      14
---------------------------------------------------------------------------
  666-  680 (17.15/ 9.49)	..............RSLFEEVSRNNVQLK
  681-  709 (16.16/ 8.37)	DVTmllsekdkaqvKETMARISQQYANVD
  717-  732 (22.43/15.48)	VLT...........RNL..EGTKRLIQMK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25799 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQQKASAINNPMNLPQSQPAPLQQAQVPPSSMGQGGFPQAPIQSQPQQQQQQQQPQQPQQLQQPQGQRRPRSSPVMQQPVPASAMNQQMYAQNMQQKSAPVQAANPVPQVRPAPLALAGGMPPL
2) EIHNAHFQHALRQHQQQKLLQLQRMNNTAGNDGVGQLGGENNQSLGSAGNFS
3) NAGNMANMGNMNNMNNMKMNNMNNLGGMNNMSMKNVNNSNNMANMGNVAGGMSNMGNMAMNDVNRQIPRNAMGAHGPQIQQQNGYVGVNKAQNSQNQQQQQQQQQQQPAGRVQMPQAKQQQQISTPASNQAIPVGQQQQAAKTPNIQITSQDLL
4) SDDEQDKGSGGTSAGNGSTTELKALTQSPLS
5) SKQQQQQQQQQHPPNRPQNEPIPQRMNQMGPQGHFPTNPPGVQHNVVPHSQPVFNAQGVSGQMGIPQSQQQQQQQQQHFARNSVSAPIPQQEWQNNSGTMASQNNPLASSPNMPQAGSPLQAPPQAVGKSGAKVPTKKNIAAGNRRRSTKGAGTPAAGAPTPASLANAIKTPHSISTPQMPPAQSNKGTPMGVSPNSEAKLAAQNEQMPFGGEMFGANGMDSDLMKRRELS
6) YLRMIKQKVTQLRSGLMNNPNAQMASNVGPPQNDMGLQNGNFYNQGRQQMSPMRNNLVPQQQQHQQHQQQQQQQQQQQQQQQPQQKQQSQPQQQQQQQPNRLSRSQPSASQSLQPTQQQI
534
238
335
1024
775
67
657
289
488
1054
1005
186










Molecular Recognition Features






MoRF SequenceStartStop




1) EPLEYDEWVTWFKGLQET
1141
1158