<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25740

Description Uncharacterized protein
SequenceMSISSDEVNFLVYRYLQESGFTHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEISINEDGTILDNRGIEALSLIDAVMPDVVQSRSQALREKIAAEKVANAAKAEAQINGEDTTNNVDTNHVDAMEVDGTMEIPPSKATVLRGHESEVFICAWNPTSDMLASGSGDSTARIWNLTANNNSANQLVLRHCIREGGQEVPSNKDVTSLDWNSEGTLLATGSYDGFARIWSTDGRLVTTLGQHKGPIFALKWNKKGNYLLSAGVDKTTIIWDAHSGEAKQQFPFHSAPALDVDWQSNTSFASCSTDMCIHVCKLGMDKPIKTFQGHSNEVNAIKWDPSGTLLASCSDDMTLKIWSMKQESCVHDLQAHTKEIYTIKWSPTGPGTNNPNAQLMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGQLVHSYRGTGGIFEVCWNSTGDRVGASASDGSVSMPYVIQ
Length499
PositionTail
OrganismBranchiostoma floridae (Florida lancelet) (Amphioxus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Cephalochordata> Leptocardii> Amphioxiformes> Branchiostomidae> Branchiostoma.
Aromaticity0.08
Grand average of hydropathy-0.265
Instability index35.31
Isoelectric point5.23
Molecular weight54328.12
Publications
PubMed=18563158

Function

Annotated function 
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central

GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central

GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25740
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     117.30|      17|      19|     218|     234|       1
---------------------------------------------------------------------------
  163-  177 (23.92/12.32)	........WNP.TSD.........ML.ASGSGDS
  255-  273 (20.62/ 9.58)	FA....lkWNK.KGN.........YL.LSAGVDK
  342-  355 (19.39/ 8.55)	........WDP.SGT.........LL.ASCSDD.
  384-  407 (17.33/ 6.84)	........WSP.TGPgtnnpnaqlML.ASASFDS
  450-  467 (16.46/ 6.11)	CV....hiWNTqSGQ.........LV...HSYRG
  468-  490 (19.59/ 8.72)	TGgifevcWNS.TGD.........RVgASAS.DG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.88|      30|      81|     202|     231|       2
---------------------------------------------------------------------------
  202-  231 (52.57/30.82)	EGGQEVP.SNKDVTSLDWNSEGTLLATGSYD
  284-  313 (46.44/26.43)	EAKQQFPfHSAPALDVDWQSN.TSFASCSTD
  426-  448 (33.87/17.44)	........HQEPVYSVAFSPDGKYLASGSFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.58|      38|      52|      61|     100|       3
---------------------------------------------------------------------------
   61-  100 (54.01/47.02)	EAEISIN.EDGT.ILDNRGIEALSlIDAVMpDVVQSRSQALR
  113-  152 (56.57/38.64)	KAEAQINgEDTTnNVDTNHVDAME.VDGTM.EIPPSKATVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.73|      16|      54|     357|     372|       5
---------------------------------------------------------------------------
  357-  372 (29.99/20.34)	TLKIWSMKQESCVHDL
  408-  423 (29.74/20.11)	TVRLWDVERGVCIHTL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25740 with Med16 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) VSMPYVIQ
492
499