<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25740

Description Uncharacterized protein
SequenceMSISSDEVNFLVYRYLQESGFTHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYVEAEISINEDGTILDNRGIEALSLIDAVMPDVVQSRSQALREKIAAEKVANAAKAEAQINGEDTTNNVDTNHVDAMEVDGTMEIPPSKATVLRGHESEVFICAWNPTSDMLASGSGDSTARIWNLTANNNSANQLVLRHCIREGGQEVPSNKDVTSLDWNSEGTLLATGSYDGFARIWSTDGRLVTTLGQHKGPIFALKWNKKGNYLLSAGVDKTTIIWDAHSGEAKQQFPFHSAPALDVDWQSNTSFASCSTDMCIHVCKLGMDKPIKTFQGHSNEVNAIKWDPSGTLLASCSDDMTLKIWSMKQESCVHDLQAHTKEIYTIKWSPTGPGTNNPNAQLMLASASFDSTVRLWDVERGVCIHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGQLVHSYRGTGGIFEVCWNSTGDRVGASASDGSVSMPYVIQ
Length499
PositionTail
OrganismBranchiostoma floridae (Florida lancelet) (Amphioxus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Cephalochordata> Leptocardii> Amphioxiformes> Branchiostomidae> Branchiostoma.
Aromaticity0.08
Grand average of hydropathy-0.265
Instability index35.31
Isoelectric point5.23
Molecular weight54328.12
Publications
PubMed=18563158

Function

Annotated function
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central
GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central
GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP25740
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     117.30|      17|      19|     218|     234|       1
---------------------------------------------------------------------------
  163-  177 (23.92/12.32)	........WNP.TSD.........ML.ASGSGDS
  255-  273 (20.62/ 9.58)	FA....lkWNK.KGN.........YL.LSAGVDK
  342-  355 (19.39/ 8.55)	........WDP.SGT.........LL.ASCSDD.
  384-  407 (17.33/ 6.84)	........WSP.TGPgtnnpnaqlML.ASASFDS
  450-  467 (16.46/ 6.11)	CV....hiWNTqSGQ.........LV...HSYRG
  468-  490 (19.59/ 8.72)	TGgifevcWNS.TGD.........RVgASAS.DG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     132.88|      30|      81|     202|     231|       2
---------------------------------------------------------------------------
  202-  231 (52.57/30.82)	EGGQEVP.SNKDVTSLDWNSEGTLLATGSYD
  284-  313 (46.44/26.43)	EAKQQFPfHSAPALDVDWQSN.TSFASCSTD
  426-  448 (33.87/17.44)	........HQEPVYSVAFSPDGKYLASGSFD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.58|      38|      52|      61|     100|       3
---------------------------------------------------------------------------
   61-  100 (54.01/47.02)	EAEISIN.EDGT.ILDNRGIEALSlIDAVMpDVVQSRSQALR
  113-  152 (56.57/38.64)	KAEAQINgEDTTnNVDTNHVDAME.VDGTM.EIPPSKATVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.73|      16|      54|     357|     372|       5
---------------------------------------------------------------------------
  357-  372 (29.99/20.34)	TLKIWSMKQESCVHDL
  408-  423 (29.74/20.11)	TVRLWDVERGVCIHTL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP25740 with Med16 domain of Kingdom Metazoa

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