<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25737

Description Uncharacterized protein
SequenceMENALDILKSLKELPMTLDILQKTRIGMSVNNLRKSSNSEEVNSLAKSLIKSWKKLLNQNGAPKRSDSTSSEPSEKSPPEGTKLQRQDSSSTAGSSFSSSQDSFPAVTKTHDSVREKCREMLANALKTDEFKNTEMKYKTRVRSRIANLKDAKNPGLREKVLHGDVSAEKMAKMTAEEMASPEMKELRQSLTKEAIRDAQMATTGGTQTDLLKCGKCKKRNVTYNQVQTRSADEPMTTFCYCNECGNRWKENALDILKSLKELPMTLDILQKTRIGMSVNNLRKSSNSEEVNSLAKSLIKSWKKLLNQNGAPKRSDSTSSEPSEKSPPEGTKLQRQDSSSTAGSSFSSSQDSFPAVTKTHDSVREKCREMLANALKTDEFKNTEMKYKTRVRSRIANLKDAKNPGLREKVLHGDVSAEKMAKMTAEEMASPEMKELRQSLTKEAIRDAQMATTGGTQTDLLKCGKCKKRNVTYNQVQTRSADEPMTTFCYCNECGNRWKATKTLRCRCIRIITPPCMIYHNAVIISSRTVVATAPEGSIRPKSSLSSDATASADRLSGAEIRRDAGGIACLAQVPRAQTAGVATATGG
Length588
PositionUnknown
OrganismBranchiostoma floridae (Florida lancelet) (Amphioxus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Cephalochordata> Leptocardii> Amphioxiformes> Branchiostomidae> Branchiostoma.
Aromaticity0.03
Grand average of hydropathy-0.752
Instability index56.06
Isoelectric point9.52
Molecular weight64879.20
Publications
PubMed=18563158

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
nucleic acid binding	GO:0003676	IEA:InterPro
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25737
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     230.52|      25|      25|      55|      79|       1
---------------------------------------------------------------------------
   31-   50 (25.25/11.71)	.....NNLRKSSNSEEVNSLAKSLI
   55-   79 (48.50/29.65)	KLLNQNGAPKRSDSTSSEPSEKSPP
   83-  105 (41.51/24.26)	KLQRQDSSSTAGSSFSS..SQDSFP
  280-  299 (25.25/11.71)	.....NNLRKSSNSEEVNSLAKSLI
  304-  328 (48.50/29.65)	KLLNQNGAPKRSDSTSSEPSEKSPP
  332-  354 (41.51/24.26)	KLQRQDSSSTAGSSFSS..SQDSFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     194.35|      25|      25|     196|     220|       2
---------------------------------------------------------------------------
  196-  220 (49.37/33.70)	IRDAQMATTGGTQ..TDLLKCGKCKKR
  222-  248 (47.81/32.40)	VTYNQVQTRSADEpmTTFCYCNECGNR
  445-  469 (49.37/33.70)	IRDAQMATTGGTQ..TDLLKCGKCKKR
  471-  497 (47.81/32.40)	VTYNQVQTRSADEpmTTFCYCNECGNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     170.60|      23|      23|     117|     139|       3
---------------------------------------------------------------------------
  117-  139 (46.93/25.87)	KCREMLANALKTDEFKNTEMKYK
  141-  160 (38.37/20.02)	RVRSRIAN.LK..DAKNPGLREK
  366-  388 (46.93/25.87)	KCREMLANALKTDEFKNTEMKYK
  390-  409 (38.37/20.02)	RVRSRIAN.LK..DAKNPGLREK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     217.17|      82|     247|       2|     195|       4
---------------------------------------------------------------------------
    2-  195 (108.59/67.55)	ENALDILKSLKELPMTLDILQKTRIGMSVnnlrkssnseevnslaksliKSWKkllnqngapkrsdstssepseksppEGTklqrqdssstagssfsssqdsfpAVTKTHDSVREkcremlanalktdefkntemkyktrvrsrianlkdaknpglrekVLHGDVSAEKMAKMTAEEMASPEMKELRQSLTKEA
  251-  444 (108.59/67.55)	ENALDILKSLKELPMTLDILQKTRIGMSVnnlrkssnseevnslaksliKSWKkllnqngapkrsdstssepseksppEGTklqrqdssstagssfsssqdsfpAVTKTHDSVREkcremlanalktdefkntemkyktrvrsrianlkdaknpglrekVLHGDVSAEKMAKMTAEEMASPEMKELRQSLTKEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.23|      17|      19|     551|     567|       6
---------------------------------------------------------------------------
  551-  567 (27.91/16.10)	ASADRLSGAEIRRDAGG
  572-  588 (28.32/16.43)	AQVPRAQTAGVATATGG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25737 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DEFKNTEMKYKTRVRSRIANLKDAKNPGLREKVLHGDVSAEKMAKMTAEEMASPEMKELRQSLTKEAIRDAQ
2) DEFKNTEMKYKTRVRSRIANLKDAKNPGLREKVLHGDVSAEKMAKMTAEEMASPEMKELRQSLTKEAIRDAQ
3) LLNQNGAPKRSDSTSSEPSEKSPPEGTKLQRQDSSSTAGSSFSSSQDSFPAVTKTHDSVREKCREMLANAL
4) LLNQNGAPKRSDSTSSEPSEKSPPEGTKLQRQDSSSTAGSSFSSSQDSFPAVTKTHDSVREKCREMLANAL
129
378
56
305
200
449
126
375










Molecular Recognition Features






MoRF SequenceStartStop




1) AKSLIKSWKKLL
2) IKSWKKL
46
299
57
305