<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP25725

Description Uncharacterized protein
SequenceMNANPQQIKDRLLQAIDKDANIVDMEGVVEVVSALEKTTMTKDALEKTRLGKYVNDVRRKTNNADLAKRLKQLVRIWQKLIIAGDIQAQDTPSNQGVSPKIAMTRPGISPKLPSKLAEVRPGASSSASAVLEKTNSANRKRRKVSLDGDEGPKPKRPATPSQAVPINGLPRGRDSPVPSPLAGRRNHSPAAALNRKPQSPAFADRRPNSPAVASTKVRSNSPALGARKLTPGSPAVAGSLRKTSSPVGNLRKTSSPVGSLRKTSSPVGSIRKTSSPVGSIRKTTSPVQFVPSGQLLHDSNTFDTPPPTPDLTSTKSLPTNITSASVGSPRPLSLALPPELANRDCGSKMKELEELSPVLPVKLRLPSTSETLSASEPPGAQSSGKAEGKKKSKSSKKKDKSKNKEPVEDSPEESSSEVKPAKRVKLKQRSLTFDPVTRQIVPNVPQSPAVTVSVSYDNEFVPRPVDLGPFPFPAALAARGQYPGLSRDLQQPMAAGKSSHSSISRPITDEAARERELKRQRALELIKAAEGEPRPGVDRPVSDEDLQRLSSEQWPGVSGCFDDNGDWRDWTDCCEKGSCEDGLLQVLPYVILD
Length593
PositionUnknown
OrganismBranchiostoma floridae (Florida lancelet) (Amphioxus)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Cephalochordata> Leptocardii> Amphioxiformes> Branchiostomidae> Branchiostoma.
Aromaticity0.03
Grand average of hydropathy-0.684
Instability index65.53
Isoelectric point9.89
Molecular weight63676.47
Publications
PubMed=18563158

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
positive regulation of gene expression	GO:0010628	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP25725
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     173.77|      27|      27|     231|     257|       1
---------------------------------------------------------------------------
  154-  181 (26.76/ 8.67)	PK...RPAtpsqavpINGLPRGRDSPV......PSPL
  207-  228 (23.32/ 6.61)	PN...SPA.......VASTKVRSNSPALGARK.....
  231-  256 (46.00/20.17)	PG...SPA.......VAGSLRKTSSPVGNLRKTSSP.
  268-  287 (26.72/ 8.64)	.................GSIRKTSSPVGSIRKTTSPV
  337-  358 (23.96/ 6.99)	.....PPE.......LAN..RDCGSKMKELEEL.SPV
  378-  407 (27.01/ 8.82)	PGaqsSGK.......AEGKKKSKSSKKKDKSKNKEPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.55|      24|      70|     462|     486|       2
---------------------------------------------------------------------------
  307-  328 (21.16/ 7.01)	PTP.DLtstKSLPTNITSASVGS.....
  462-  486 (42.54/24.77)	PRPvDL...GPFPFPAALAARGQYPGLS
  487-  504 (26.86/10.79)	.R..DL...QQ...PMA.AGKSSHSSIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      31.93|      10|      26|     505|     519|       8
---------------------------------------------------------------------------
  505-  519 (12.81/17.07)	RPITDEaarerELKR
  539-  548 (19.12/ 9.85)	RPVSDE.....DLQR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP25725 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LGPFPFPAALAARGQYPGLSRDLQQPMAAGKSSHSSISRPITDEAARE
2) QAQDTPSNQGVSPKIAMTRPGISPKLPSKLAEVRPGASSSASAVLEKTNSANRKRRKVSLDGDEGPKPKRPATPSQAVPINGLPRGRDSPVPSPLAGRRNHSPAAALNRKPQSPAFADRRPNSPAVASTKVRSNSPALGARKLTPGSPAVAGSLRKTSSPVGNLRKTSSPVGSLRKTSSPVGSIRKTSSPVGSIRKTTSPVQFVPSGQLLHDSNTFDTPPPTPDLTSTKSLPTNITSASVGSPRPLSLALPPELANRDCGSKMKELEELSPVLPVKLRLPSTSETLSASEPPGAQSSGKAEGKKKSKSSKKKDKSKNKEPVEDSPEESSSEVKPAKRVKLKQRSLTFDPVTRQIVPNVPQSPA
467
87
514
449










Molecular Recognition Features






MoRF SequenceStartStop




1) KRVKLKQRSLTFDPVTRQIV
422
441